乙酰化组蛋白H1抗体上海沪震实业有限公司

性能参数

产品名称: 乙酰化组蛋白H1抗体
英文名称: Histone H1 (acetyl K25)
抗体货号: hz-17415R
产品规格: 100ul
级    别: , , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 1580元
抗原: IgG
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 见说明书
应用范围: ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500
更新时间: 2018/4/18 16:42:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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产品详细描述

 Rabbit Anti-Histone H1 (acetyl K25) antibody

 

产品编号 hz-17415R
英文名称 Histone H1 (acetyl K25)
中文名称 乙酰化组蛋白H1抗体
别    名 H10; H10_HUMAN; h1f0; H1FV; Histone H1''; Histone H1(0); Histone H10; Histone H5; MGC5241; N-terminally processed.  
   
产品类型 乙酰化抗体 
研究领域 细胞生物  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Sheep, 
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 21kDa
细胞定位 细胞核 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated Synthesised acetylpeptide derived from human Histone H1 around the acetylation site of K25: 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-independent histone that is a member of the histone H1 family. [provided by RefSeq, Oct 2015]

Function:
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell division.

Subcellular Location:
Nucleus. Chromosome. The RNA edited version has been localized to nuclear speckles. During mitosis, it appears in the vicinity of condensed chromosomes.

Post-translational modifications:
Phosphorylated on Ser-17 in RNA edited version.

Similarity:
Belongs to the histone H1/H5 family. Contains 1 H15 (linker histone H1/H5 globular) domain.

SWISS:
P07305

Gene ID:
3005

Database links:

Entrez Gene: 3005 Human

Entrez Gene: 14958 Mouse

Entrez Gene: 24437 Rat

Omim: 142708 Human

SwissProt: P07305 Human

SwissProt: P10922 Mouse

SwissProt: P43278 Rat

Unigene: 745024 Human

Unigene: 24350 Mouse

Unigene: 3129 Rat

 



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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