FITC标记的沉默驱动蛋白KIF4A抗体-抗体-抗体-生物在线
FITC标记的沉默驱动蛋白KIF4A抗体

FITC标记的沉默驱动蛋白KIF4A抗体

商家询价

产品名称: FITC标记的沉默驱动蛋白KIF4A抗体

英文名称: Anti-KIF4A/FITC

产品编号: HZ-7107R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: IF=1:50-200

上海沪震实业有限公司
  • 联系人 : 鲍丽雯
  • 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 139****0749
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  • 邮箱 : www.shzbio.net

 Rabbit Anti-KIF4A/FITC Conjugated antibody

FITC标记的沉默驱动蛋白KIF4A抗体

 

英文名称 Anti-KIF4A/FITC
中文名称 FITC标记的沉默驱动蛋白KIF4A抗体
别    名 Chromokinesin; Chromokinesin-A; Chromosome associated kinesin KIF4A; Chromosome-associated kinesin KIF4A; KIF4; KIF4 G1; KIF4-G1; KIF4A; KIF4A_HUMAN; Kinesin family member 4A.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  染色质和核信号  信号转导  细胞凋亡  细胞周期蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 140kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KIF4A
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization.
Tissue specificity: Highly expressed in hematopoietic tissues, fetal liver, spleen, thymus and adult thymus and bone marrow. Lower levels are found in heart, testis, kidney, colon and lung.

Function:
Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization. 

Subunit:
Interacts with unphosphorylated PRC1 during late mitosis. 

Subcellular Location:
Nucleus matrix. Cytoplasm, cytoskeleton, spindle. Midbody. Chromosome. Note=Not present in the nucleolus. In early mitosis, associated with the mitotic spindle, in anaphase, localized to the spindle midzone and, in telophase and cytokinesis, to the midbody. In late cytokinesis, found in the center of the midbody. Associated with chromosomes at all stages of mitosis. 

Tissue Specificity:
Highly expressed in hematopoietic tissues, fetal liver, spleen, thymus and adult thymus and bone marrow. Lower levels are found in heart, testis, kidney, colon and lung. 

Similarity:
Belongs to the kinesin-like protein family. Chromokinesin subfamily. 
Contains 1 kinesin-motor domain. 

Database links:

Entrez Gene: 24137 Human

Entrez Gene: 16571 Mouse

Entrez Gene: 84393 Rat

NCBI: 7305205 Human

Omim: 300521 Human

SwissProt: O95239 Human

SwissProt: P33174 Mouse

Unigene: 648326 Human

Unigene: 383091 Mouse

Unigene: 231889 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

在中期至后期转变过程中,PrC1转位到叉指纺锤体微管端部的运动蛋白,这是形成有组织的中心纺锤体中段和中段和成功胞质分裂的重要步骤。可能在有丝分裂染色体定位和双极纺锤体稳定中发挥作用。

 

组织特异性:在造血组织、胎儿肝脏、脾脏、胸腺和成人胸腺和骨髓中高表达。在心脏、睾丸、肾脏、结肠和肺中发现较低水平。