FITC标记的磷酸化组胺受体H1抗体上海沪震实业有限公司

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产品名称: FITC标记的磷酸化组胺受体H1抗体
英文名称: Anti-phospho-HRH1(Ser398)/FITC
抗体货号: HZ-6665R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: IF=1:50-200
更新时间: 2018/8/27 14:42:00
详细资料:  实验方法技术资料
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诚信指数:932点
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
地址:
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邮编:
200612
电话:
021-60345367
传真:
021-31320307
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陈先生
所在区域:
上海·中国-上海
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产品详细描述

 Rabbit Anti-phospho-HRH1(Ser398)/FITC Conjugated antibody 

 

FITC标记的***酸化组胺受体H1抗体
英文名称 Anti-phospho-HRH1(Ser398)/FITC
中文名称 FITC标记的***酸化组胺受体H1抗体
别    名 HRH1 (phospho S398); p-HRH1 (phospho S398); HRH1(phospho S398); H1R; HisH1; Histamine H1 receptor; Histamine receptor H1; Histamine receptor subclass H1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
产品类型 ***酸化抗体 
研究领域 细胞生物  信号转导  生长因子和***  转录调节因子  G蛋白偶联受体  G蛋白信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Guinea Pig, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 54kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human HRH1 around the phosphorylation site of Ser398 [SH(p-S)RQ]
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].

Function:
In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Post-translational modifications:
Potential sites of phosphorylation in the third cytoplasmic loop may play an important role in regulating signal transduction through the receptor molecule.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 3269 Human

Entrez Gene: 15465 Mouse

Omim: 600167 Human

SwissProt: P35367 Human

SwissProt: P70174 Mouse

Unigene: 1570 Human

Unigene: 333327 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application

 

Histamine是从肥大细胞、肠嗜铬样细胞和神经元释放出来的普遍存在的信使分子。它的各种作用是由组胺受体H1、H2、H3和H4介导的。这个基因直到最近才被认为是无内含物。该基因编码的蛋白是一种完整的膜蛋白,属于G蛋白偶联受体超家族。它介导了平滑肌的收缩,毛细血管通透性增加,由于终末小叶收缩,儿茶酚胺从肾上腺髓质的释放,以及中枢神经系统的神经传递。多个交替剪接变异体,编码相同的蛋白质,已被鉴定。[ RefSeq,JUL 2008 ]提供。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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