FITC标记的组胺受体H2抗体
产品名称: FITC标记的组胺受体H2抗体
英文名称: Anti-HRH2/FITC
产品编号: HZ-6664R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-HRH2/FITC Conjugated antibody
FITC标记的组胺受体H2抗体
英文名称 | Anti-HRH2/FITC |
中文名称 | FITC标记的组胺受体H2抗体 |
别 名 | Gastric receptor 1; Gastric receptor Iv H2R; HGNC:5183; HH2R; Histamine H2 receptor; Histamine receptor H2; HRH2; HRH2_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 信号转导 转录调节因子 激酶和磷酸酶 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Rabbit, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 40kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human HRH2 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: The HRH2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway. Function: The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway (By similarity). Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 3274 Human Entrez Gene: 15466 Mouse Entrez Gene: 25461 Rat Omim: 142703 Human SwissProt: P25021 Human SwissProt: P97292 Mouse SwissProt: P25102 Rat Unigene: 247885 Human Unigene: 57243 Mouse Unigene: 138113 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
组胺受体的HRH2亚类介导胃酸分泌。似乎也调节胃肠动力和肠道分泌。可能在调节细胞生长和分化中起作用。该受体的活性由激活腺苷酸环化酶的G蛋白介导,并通过单独的G蛋白依赖的机制,磷酸肌醇/蛋白激酶(PKC)信号通路。