FITC标记的单氨氧化酶A抗体
产品名称: FITC标记的单氨氧化酶A抗体
英文名称: Anti-MAOA/FITC
产品编号: HZ-6679R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-MAOA/FITC Conjugated antibody
FITC标记的单氨氧化酶A抗体
英文名称 | Anti-MAOA/FITC |
中文名称 | FITC标记的单氨氧化酶A抗体 |
别 名 | Amine oxidase [flavin containing] A; EC 1.4.3.4; MAO A; MAO-A; Maoa; Monoamine oxidase A; Monoamine oxidase type A; AOFA_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 神经生物学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 60kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MAOA |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Monoamine oxidase A (MAO-A) catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAO-A preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine. Defects in MAOA are a cause of Brunner syndrome which is a form of X-linked nondysmorphic mild mental retardation. Function: Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine. Subcellular Location: Mitochondrion outer membrane. Tissue Specificity: Heart, liver, duodenum, blood vessels and kidney. DISEASE: Defects in MAOA are the cause of Brunner syndrome (BRUNS) [MIM:300615]. Brunner syndrome is a form of X-linked non-dysmorphic mild mental retardation. Male patients are affected by a syndrome of borderline mental retardation and exhibit abnormal behavior, including disturbed regulation of impulsive aggression. Obligate female carriers have normal intelligence and behavior. Similarity: Belongs to the flavin monoamine oxidase family. Database links: Entrez Gene: 4128 Human Entrez Gene: 17161 Mouse Entrez Gene: 29253 Rat Omim: 309850 Human SwissProt: P21397 Human SwissProt: Q64133 Mouse SwissProt: P21396 Rat Unigene: 183109 Human Unigene: 21108 Mouse Unigene: 224544 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
Monoamine oxidase A(MAO-A)催化生物和外源性胺的氧化脱氨作用,在中枢神经系统和外周组织中的神经活性和血管活性胺的代谢中具有重要的功能。MAO-A优先氧化生物胺,如5-羟色胺(5-HT)、去甲肾上腺素和肾上腺素。MAOA的缺陷是布鲁纳综合征的一个原因,它是X连锁的非易失性轻度精神发育迟滞的一种形式。