FITC标记的单氨氧化酶A抗体-抗体-抗体-生物在线
FITC标记的单氨氧化酶A抗体

FITC标记的单氨氧化酶A抗体

商家询价

产品名称: FITC标记的单氨氧化酶A抗体

英文名称: Anti-MAOA/FITC

产品编号: HZ-6679R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: IF=1:50-200

上海沪震实业有限公司
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 Rabbit Anti-MAOA/FITC Conjugated antibody 

FITC标记的单氨氧化酶A抗体

 

英文名称 Anti-MAOA/FITC
中文名称 FITC标记的单氨氧化酶A抗体
别    名 Amine oxidase [flavin containing] A; EC 1.4.3.4; MAO A; MAO-A; Maoa; Monoamine oxidase A; Monoamine oxidase type A; AOFA_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MAOA
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Monoamine oxidase A (MAO-A) catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAO-A preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine. Defects in MAOA are a cause of Brunner syndrome which is a form of X-linked nondysmorphic mild mental retardation.

Function:
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine.

Subcellular Location:
Mitochondrion outer membrane.

Tissue Specificity:
Heart, liver, duodenum, blood vessels and kidney.

DISEASE:
Defects in MAOA are the cause of Brunner syndrome (BRUNS) [MIM:300615]. Brunner syndrome is a form of X-linked non-dysmorphic mild mental retardation. Male patients are affected by a syndrome of borderline mental retardation and exhibit abnormal behavior, including disturbed regulation of impulsive aggression. Obligate female carriers have normal intelligence and behavior.

Similarity:
Belongs to the flavin monoamine oxidase family.

Database links:

Entrez Gene: 4128 Human

Entrez Gene: 17161 Mouse

Entrez Gene: 29253 Rat

Omim: 309850 Human

SwissProt: P21397 Human

SwissProt: Q64133 Mouse

SwissProt: P21396 Rat

Unigene: 183109 Human

Unigene: 21108 Mouse

Unigene: 224544 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

Monoamine oxidase A(MAO-A)催化生物和外源性胺的氧化脱氨作用,在中枢神经系统和外周组织中的神经活性和血管活性胺的代谢中具有重要的功能。MAO-A优先氧化生物胺,如5-羟色胺(5-HT)、去甲肾上腺素和肾上腺素。MAOA的缺陷是布鲁纳综合征的一个原因,它是X连锁的非易失性轻度精神发育迟滞的一种形式。