FITC标记的干细胞转录因子NANOGP8抗体
产品名称： FITC标记的干细胞转录因子NANOGP8抗体
英文名称： Anti-NANOGP8/FITC
产品编号： HZ-6552R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-NANOGP8/FITC Conjugated antibody
| FITC标记的干细胞转录因子NANOGP8抗体 |
| 英文名称 | Anti-NANOGP8/FITC |
| 中文名称 | FITC标记的干细胞转录因子NANOGP8抗体 |
| 别 名 | Homeobox protein NANOGP8; MGC119250; NANOG; Nanog homeobox pseudogene 8; NANOGP 8; NANOGP1; NANOGP8; NANP8_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 染色质和核信号 转录调节因子 肿瘤细胞生物标志物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Chicken, Dog, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 34kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NANOGP8 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self-renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT-PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a recombinant NANOGP8 protein have shown that the protein localizes to the nucleus and can promote cell proliferation, similar to NANOG. [provided by RefSeq, Sep 2009] Function: May act as a transcription regulator. When overexpressed, promotes entry of cells into S phase and cell proliferation. Subcellular Location: Nucleus. Tissue Specificity: Expressed in osteosarcoma cancer cell line (at protein level). breast and urinary bladder tissues, and also osteosarcoma, hepatoma, and breast adenocarcinoma cancer cell lines. Similarity: Belongs to the Nanog homeobox family. Contains 1 homeobox DNA-binding domain. Database links: Entrez Gene: 388112 Human SwissProt: Q6NSW7 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该位点是转录因子NANG的处理假基因。NANG在调节多能干细胞和肿瘤细胞的自我更新中起着中心作用。这个假基因包含一个完整的开放阅读框，可以潜在地编码类似于NANG的蛋白质。虽然没有从这种假基因转录的证据，RT-PCR研究表明，NANGP8可以在一些癌细胞系中表达。使用重组NANOP8蛋白的体外研究表明，该蛋白定位于细胞核，并能促进细胞增殖，类似于NANG。[ RefSeq，SEP 2009提供]