FITC标记的磷酸化S6核糖体蛋白抗体上海沪震实业有限公司

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产品名称: FITC标记的磷酸化S6核糖体蛋白抗体
英文名称: Anti-Phospho-RPS6 (Ser235+Ser236)/FITC
抗体货号: HZ-3388R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: IF=1:50-200
更新时间: 2018/8/9 11:31:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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产品详细描述

 Rabbit Anti-Phospho-RPS6 (Ser235+Ser236)/FITC Conjugated antibody 

FITC标记的***酸化S6核糖体蛋白抗体

 

英文名称 Anti-Phospho-RPS6 (Ser235+Ser236)/FITC
中文名称 FITC标记的***酸化S6核糖体蛋白抗体
别    名 RPS6 (phospho S235 + S236); p-RPS6 (phospho S235 + S236); Air8; DS6; Hemocytes enlarged; Hen; L(1)AIR8; Lethal (1) haemocytes enlarged; Lethal aberrant immune response 8; Lethal(1)abberant immune response[8]; Phosphoprotein NP33; Pp30; Ribosomal protein S6; RP S6; RPS 6; RpS6; RS6; RS6_HUMAN; S6; S6 Ribosomal Protein.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
产品类型 ***酸化抗体 
研究领域 肿瘤  免疫学  染色质和核信号  信号转导  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Rabbit, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 27kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human S6 Ribosomal Protein around the phosphorylation site of Ser235/236
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Function:
May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA.

Post-translational modifications:
Ribosomal protein S6 is the major substrate of protein kinases in eukaryote ribosomes. The phosphorylation is stimulated by growth factors, tumor promoting agents, and mitogens. It is dephosphorylated at growth arrest. Phosphrylated at Ser-235 and Ser-236 by RPS6KA1 and RPS6KA3; phosphorylation at these sites facilitates the assembly of the preinitiation complex.

Similarity:
Belongs to the ribosomal protein S6e family.

Database links:

Entrez Gene: 6194 Human

Entrez Gene: 20104 Mouse

Entrez Gene: 667739 Mouse

Entrez Gene: 29304 Rat

Omim: 180460 Human

SwissProt: P62753 Human

SwissProt: P62754 Mouse

SwissProt: P62755 Rat

Unigene: 408073 Human

Unigene: 379007 Mouse

Unigene: 425090 Mouse

Unigene: 34341 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application
   

Ribosomes,催化蛋白质合成的细胞器,由一个小的40S亚基和一个大的60S亚基组成。这些亚基由4种RNA和大约80种结构上不同的蛋白质组成。该基因编码细胞质核糖体蛋白,其是40S亚基的一个组成部分。该蛋白属于核糖体蛋白的S6E家族。它是核糖体中蛋白激酶的主要底物,具有不同的蛋白激酶***酸化的五个C-末端丝氨酸残基的子集。***酸化是由广泛的刺激,包括生长因子、促肿瘤剂和有丝分裂原引起的。脱***作用发生在生长停滞期。通过选择性翻译特定的mRNA,该蛋白可能有助于细胞生长和增殖的控制。对于编码核糖体蛋白的基因来说是典型的,这种基因的多个假基因通过基因组分散。[ RefSeq,JUL 2008 ]

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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