FITC标记的驱动蛋白家族KIF17抗体上海沪震实业有限公司

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产品名称: FITC标记的驱动蛋白家族KIF17抗体
英文名称: Anti-KIF17/FITC
抗体货号: HZ-3527R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: IF=1:50-200
更新时间: 2018/8/10 9:10:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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上海·中国-上海
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产品详细描述

 Rabbit Anti-KIF17/FITC Conjugated antibody

FITC标记的驱动蛋白家族KIF17抗体

 

英文名称 Anti-KIF17/FITC
中文名称 FITC标记的驱动蛋白家族KIF17抗体
别    名 KIAA1405; KIF 17; KIF 17B; KIF 3X; KIF17B; KIF3-related motor protein; KIF3X; Kinesin family member 17; Kinesin like protein KIF 17; Kinesin like protein KIF17; KIF17_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  免疫学  神经生物学  信号转导  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 115kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KIF17
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The kinesin superfamily of proteins (KIFs) consists of a class of microtubule-dependent motors that play a major role in many cellular and developmental functions, including organelle transport, mitosis, meiosis, and possibly long-range signaling in neurons. The kinesin proteins are involved in organelle transport and are primarily associated with anterograde transport of vesicles and organelles in neurons, epithelial cells, and melanosomes with bidirectional transport of mitochondria. They also mediate transport between the endoplasmic reticulum (ER) and the Golgi complex. In neurons, kinesin motors conduct vesicular transport, such as of synaptic vesicle components to axons and of neurotransmitter receptors to dendrites. KIF17 belongs to the functionally diverse subgroup of the kinesin superfamily characterized by a N-terminal motor domain (N-IV class), that includes the KIF3 motor protein. KIF17 is specifically expressed in the brain, present in abundance in the gray matter, particularly in the hippocampus and cerebral cortex, but not in the white matter such as the optic nerve.

Function:
Transports vesicles containing N-methyl-D-aspartate(NMDA) receptor 2B along microtubules (By similarity).

Subunit:
Interacts with LIN-10 PDZ domain. Interacts with PIWIL1(By similarity). Interacts with TBATA (By similarity). 

Subcellular Location:
Cytoplasm, cytoskeleton (Probable).

Similarity:
Belongs to the kinesin-like protein family.
Contains 1 kinesin-motor domain. 

Database links:

Entrez Gene: 57576 Human

Entrez Gene: 16559 Mouse

Omim: 605037 Human

SwissProt: Q9P2E2 Human

SwissProt: Q99PW8 Mouse

Unigene: 130411 Human

Unigene: 271936 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   
   

蛋白质的驱动蛋白超家族(KIFS)由一类微管相关的电机,在许多细胞和发育功能中发挥重要作用,包括细胞器运输,有丝分裂,减数分裂,并可能在神经元中的长程信号。驱动蛋白蛋白参与细胞器运输,主要与顺行运输的囊泡和细胞器在神经元,上皮细胞和黑素体的双向运输线粒体。它们还介导内质网(ER)和高尔基复合体之间的转运。在神经元中,驱动蛋白马达进行囊泡运输,如突触囊泡成分轴突和神经递质受体树突。KIF17属于驱动蛋白超家族的功能多样性亚组,其特征在于N-末端运动区(N-IV类),包括KIF3马达蛋白。KIF17在脑中特异表达,在灰质中大量存在,特别是在海马和大脑皮质,而在视神经等白质中不存在。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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