Rabbit Anti-Phospho-Proteinase-activated receptor 4 (Thr163)/FITC Conjugated antibody
|英文名称||Anti-Phospho-Proteinase-activated receptor 4 (Thr163)/FITC|
|别 名||PAR4(Phospho-Thr163); PAR4(Phospho-T163); p-PAR4(Thr163); p-PAR4(T163); F2RL3; F2R Like Thrombin/Trypsin Receptor 3; Coagulation Factor II (Thrombin) Receptor-Like 3; Thrombin Receptor-Like 3; PAR-4; PAR4; Coagulation Factor II Receptor-Like 3; Proteinase-Activated Receptor-4; Proteinase-Activated Receptor 4; Protease-Activated Receptor-4; PAR4_HUMAN;|
|规格价格||100ul/2980元 购买 大包装/询价|
|说 明 书||100ul|
|研究领域||肿瘤 免疫学 信号转导 细胞凋亡 转录调节因子|
|交叉反应||Human, Mouse, Rat,|
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
|分 子 量||41kDa|
|性 状||Lyophilized or Liquid|
|免 疫 原||KLH conjugated Synthesised phosphopeptide derived from human Proteinase-activated receptor 4 around the phosphorylation site of Thr163|
|纯化方法||affinity purified by Protein A|
|储 存 液||0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.|
|保存条件||Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.|
Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin. [provided by RefSeq, Jul 2008]
Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation.
Cell membrane; Multi-pass membrane protein.
Widely expressed, with highest levels in lung, pancreas, thyroid, testis and small intestine. Not expressed in brain, kidney, spinal cord and peripheral blood leukocytes. Also detected in platelets.
A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.
Belongs to the G-protein coupled receptor 1 family.
Entrez Gene: 9002 Human
Omim: 602779 Human
SwissProt: Q96RI0 Human
Unigene: 137574 Human
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
凝血因子II（凝血酶）受体样3（F2RL3）是与鸟嘌呤核苷酸结合蛋白偶联的7跨膜区受体家族的一员。F2RL3也是蛋白酶激活受体家族的成员。F2RL3通过其胞外氨基末端的蛋白水解裂解而激活。新的氨基末端起着拴系配体的作用，并激活受体。F2RL3由凝血酶和胰蛋白酶激活。[ RefSeq，JUL 2008 ]