FITC标记的APC标记小鼠抗人CD8单克隆抗体
产品名称: FITC标记的APC标记小鼠抗人CD8单克隆抗体
英文名称: Anti-human CD8-APC/FITC
产品编号: HZ-30069M-APC-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200
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Mouse Anti-human CD8-APC/FITC Conjugated antibody
FITC标记的APC标记小鼠抗人CD8单克隆抗体
英文名称 | Anti-human CD8-APC/FITC |
中文名称 | FITC标记的APC标记小鼠抗人CD8单克隆抗体 |
别 名 | CD8-b;CD 8A; CD 8B; CD8 antigen alpha polypeptide; CD8A anti; CD8a antigen an; CD8a molecule; CD8B; CD8b antigen; CD8b antigen isoform 2; CD8b molecule; CD8B protein; CD8B1; Leu2; Leu2 T lymphocyte antigen; Ly3; LYT3; MAL; MGC119115; OKT8 T Cell antigen; p32; T cell antigen Leu2; T cell surface glycoprotein CD8 alpha chain; T cell surface glycoprotein CD8 beta chain; T lymphocyte differentiation antigen T8/Leu 2; CD8A_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 免疫学 干细胞 细胞表面分子 淋巴细胞 t-淋巴细胞 b-淋巴细胞 |
抗体来源 | Mouse |
克隆类型 | Monoclonal |
交叉反应 | Human, |
产品应用 | Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 27kDa |
性 状 | Liquid |
浓 度 | 2mg/1ml |
免 疫 原 | |
亚 型 | IgG |
纯化方法 | affinity purified by Protein G |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]. Subunit: In general heterodimer of an alpha and a beta chain linked by two disulfide bonds. Can also form homodimers. Shown to be expressed as heterodimer on thymocytes and as homodimer on peripheral blood T-lymphocytes. Interacts with the MHC class I HLA-A/B2M dimer. Interacts with LCK in a zinc-dependent manner. Subcellular Location: Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
CD8抗原是细胞表面的糖蛋白上发现的最有效的细胞毒性T淋巴细胞介导的细胞与细胞间的相互作用在免疫系统。作为一个辅助受体CD8抗原对T淋巴细胞T细胞受体识别的抗原的MHC I类分子的抗原提呈细胞显示上下文。辅助受体的功能是一个同型二聚体由两个α链或是由一个α和β链的异二聚体。α和β链的份额显着同源性的免疫球蛋白轻链可变。该基因编码的CD8α链。多基因编码的不同亚型已发现这个基因。[由RefSeq提供,月2011日]。