FITC标记的翻译延伸因子EF-1 α2抗体上海沪震实业有限公司

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产品名称: FITC标记的翻译延伸因子EF-1 α2抗体
英文名称: Anti-eEF1A2/FITC
抗体货号: HZ-13054R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/9/14 9:45:00
详细资料:  实验方法技术资料
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诚信指数:1084点
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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产品详细描述

 Rabbit Anti-eEF1A2/FITC Conjugated antibody

FITC标记的翻译延伸因子EF-1 α2抗体

 

英文名称 Anti-eEF1A2/FITC
中文名称 FITC标记的翻译延伸因子EF-1 α2抗体
别    名 eEF1A 2; eEF1A-2; Eef1a2; EEF1AL; EF 1 alpha 2; EF-1-alpha-2; EF1A; EF1A2_HUMAN; Elongation factor 1 A 2; Elongation factor 1 alpha; Elongation factor 1 alpha 2; Elongation factor 1-alpha 2; Eukaryotic elongation factor 1 A-2; Eukaryotic translation elongation factor 1 alpha 2; HS1; OTTHUMP00000031776; Statin like; Statin S1; Statin-S1; STN; STNL.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  心血管  细胞生物  神经生物学  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Zebrafish, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human eEF1A2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Elongation factor 1 alpha 2 (EF-1 alpha2) is a eukaryotic protein translation factor that is expressed in terminally differentiated cells of skeletal muscle, heart, and certain areas of the brain. Along with protein synthesis, EF-1 alpha2 also plays a role in cytoskeletal remodelling and apoptosis. The gene encoding for EF-1 alpha2 maps to chromosome 20q13. Wasted (wst) refers to a spontaneous autosomal recessive mutation in which this gene is deleted, and it leads to tremors and disturbances of gait shortly after weaning, followed by motor neuron degeneration, paralysis, and death by about 28 days in mice. EF-1 alpha2 has the ability to transform mammalian cells and is highly expressed in tumors of the ovary, breast, and lung, thereby proving a good candidate for an oncogene. In addition to this, EF-1 alpha2 enhances focus formation, allows anchorage-independent growth, and decreases the doubling time of rodent fibroblasts.

Function:
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

Subunit:
Monomer

Subcellular Location:
Nucleus.

Tissue Specificity:
Brain, heart, and skeletal muscle.

Similarity:
Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.

Database links:

Entrez Gene: 1917 Human

Entrez Gene: 13628 Mouse

Entrez Gene: 24799 Rat

Entrez Gene: 101109898 Sheep

Entrez Gene: 380550 Xenopus laevis

Omim: 602959 Human

SwissProt: Q05639 Human

SwissProt: P62631 Mouse

SwissProt: P62632 Rat

Unigene: 433839 Human

Unigene: 2645 Mouse

Unigene: 9764 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

伸长因子1α2(EF-1α2)是真核蛋白质翻译因子,在骨骼肌、心脏和大脑某些区域的终末分化细胞中表达。随着蛋白质的合成,EF-1α2也在细胞骨架重塑和细胞凋亡中发挥作用。编码EF-1α2的基因定位于染色体20q13。Wasted(wst)是指一种自发的常染色体隐性突变,该基因缺失,在断奶后不久,导致小鼠的步态震颤和紊乱,随后小鼠的运动神经元变性、瘫痪和死亡约28天。EF-1α2具有转化哺乳动物细胞的能力,在卵巢、乳腺和肺的肿瘤中高度表达,从而证明是癌基因的良好候选者。除此之外,EF-1α增强病灶的形成,使锚地独立生长,降低鼠类成纤维细胞倍增时间。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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