FITC标记的肝细胞癌HHCM蛋白抗体
产品名称： FITC标记的肝细胞癌HHCM蛋白抗体
英文名称： Anti-HHCM/FITC
产品编号： HZ-15475R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-HHCM/FITC Conjugated antibody
FITC标记的肝细胞癌HHCM蛋白抗体
| 英文名称 | Anti-HHCM/FITC |
| 中文名称 | FITC标记的肝细胞癌HHCM蛋白抗体 |
| 别 名 | Hepatocellular carcinoma protein HHCM; HHC(M); Mahlavu hepatocellular carcinoma; HHCM_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 染色质和核信号 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 52kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HHCM |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: HHCM is a 467 amino acid protein that has oncogenic transforming capabilities on a variety of different cell lines. When HHCM was transfected into BRL-1 (Buffalo rat liver) or NIH3T3 cells, the cells exhibited significant morphological changes, anchorage independent growth and loss of contact inhibition. When the cells were inoculated into rats and mice, they became highly tumorigenic. HHCM gene-related DNA sequences were found in at least nineteen hepatomas of Asian origin. The gene encoding HHCM maps to human chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis. Database links: Entrez Gene: 10639 Human SwissProt: Q05877 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
HHCM是一种467个氨基酸的蛋白质，具有多种不同细胞系的致癌转化能力。将HHCM转染到BRL-1(水牛肝)或NIH3T3细胞中，细胞形态学发生显著变化，锚定生长不受抑制，接触抑制消失。当细胞接种到大鼠和小鼠时，它们变得高度致瘤性。HHCM基因相关的DNA序列在至少十九个亚洲来源的肝癌中发现。HHCM基因编码人类近8个碱基，由近1亿4600万个碱基组成，编码约800个基因。在一些白血病和淋巴瘤中发现染色体8部分移位，并伴有c-Myc基因的扩增，并且通常与较差的预后相关。