FITC标记的二氢乳清酸脱氢酶抗体
产品名称: FITC标记的二氢乳清酸脱氢酶抗体
英文名称: Anti-DHODH/FITC
产品编号: HZ-14305R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-DHODH/FITC Conjugated antibody
FITC标记的二氢乳清酸脱氢酶抗体
英文名称 | Anti-DHODH/FITC |
中文名称 | FITC标记的二氢乳清酸脱氢酶抗体 |
别 名 | DHOdehase; Dhodh; Dihydroorotate dehydrogenase (quinone); Dihydroorotate dehydrogenase; Dihydroorotate dehydrogenase mitochondrial; Dihydroorotate oxidase; Human complement of yeast URA1; mitochondrial; PYRD_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 信号转导 细胞骨架 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 43kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human DHODH |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. [provided by RefSeq, Jul 2008] Function: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Subcellular Location: Mitochondrion inner membrane. Post-translational modifications: The uncleaved transit peptide is required for mitochondrial targeting and proper membrane integration. DISEASE: Defects in DHODH are the cause of postaxial acrofacial dysostosis (POADS) [MIM:263750]; also known as Miller syndrome. POADS is characterized by severe micrognathia, cleft lip and/or palate, hypoplasia or aplasia of the posterior elements of the limbs, coloboma of the eyelids and supernumerary nipples. POADS is a very rare disorder: only 2 multiplex families, each consisting of 2 affected siblings born to unaffected, nonconsanguineous parents, have been described among a total of around 30 reported cases. Similarity: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. Database links: Entrez Gene: 1723 Human Entrez Gene: 533873 Cow Entrez Gene: 610755 Dog Entrez Gene: 56749 Mouse Entrez Gene: 65156 Rat Entrez Gene: 494065 Zebrafish Omim: 126064 Human SwissProt: Q02127 Human SwissProt: O35435 Mouse SwissProt: Q63707 Rat Unigene: 654427 Human Unigene: 23894 Mouse Unigene: 81502 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码的蛋白催化了新嘧啶生物合成中的第四个酶学步骤,泛醌介导的二氢氟酸盐氧化为氟酸盐。这种蛋白质是位于线粒体内膜的外表面的线粒体蛋白。[ RefSeq,JUL 2008 ]