FITC标记的微管蛋白折叠辅助因子E样抗体
产品名称： FITC标记的微管蛋白折叠辅助因子E样抗体
英文名称： Anti-TBCEL/FITC
产品编号： HZ-10292R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
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- 邮箱 : www.shzbio.net
Rabbit Anti-TBCEL/FITC Conjugated antibody
FITC标记的微管蛋白折叠辅助因子E样抗体
| 英文名称 | Anti-TBCEL/FITC |
| 中文名称 | FITC标记的微管蛋白折叠辅助因子E样抗体 |
| 别 名 | EL; Leucine-rich repeat-containing protein 35; LRRC35; TBCEL; TBCEL_HUMAN; Tubulin folding cofactor E-like; Tubulin-specific chaperone cofactor E-like protein. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 48kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TBCEL |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: TBCEL is a 424 amino acid cytoplasmic protein that acts as a regulator of tubulin stability. While abundantly expressed in testis, TBCEL is also present in several tissues at a much lower level. TBCEL contains seven LRR (leucine-rich) repeats, one LRRCT domain and one ubiquitin-like domain. The gene that encodes TBCEL consists of 66,704 bases and maps to human chromosome 11q23.3. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that map to chromosome 11. Function: Acts as a regulator of tubulin stability. Subcellular Location: Cytoplasm > cytoskeleton. Tissue Specificity: Abundantly expressed in testis, but is also present in several tissues at a much lower level. Similarity: Contains 7 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 ubiquitin-like domain. Database links: Entrez Gene: 219899 Human Omim: 610451 Human SwissProt: Q5QJ74 Human Unigene: 504136 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
TBCEL是作为微管蛋白稳定性调节的424氨基酸胞质蛋白。在睾丸中大量表达时，TBCEL也存在于许多组织中，在低得多的水平上。TBCEL包含七个LRR（亮氨酸富集）重复序列，一个LRRCT结构域和一个泛素样结构域。编码TBCEL的基因由66704个碱基组成，并映射到人类染色体11q23.3。11号染色体含有1400个以上的基因，几乎包含了4%的人类基因组。Jevl和Lange Nielsen综合征、杰克布森综合征、尼曼匹克病、遗传性血管水肿和Smith-LeMi-Opz综合征