Anti-NKG2C抗体-抗体-抗体-生物在线
Anti-NKG2C抗体

Anti-NKG2C抗体

商家询价

产品名称: Anti-NKG2C抗体

英文名称: NKG2C

产品编号: YB--2416R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-NKG2C抗体

产品编号 YB-2416R
英文名称 NKG2C
中文名称 NK细胞受体2C抗体
别    名 Natural killer cell group 2C; natural killer cell protein group 2-C; NKG2-C type II integral membrane protein; NKG2-C-activating NK receptor; NK cell receptor C; CD159 antigen-like family member C; CD159c; KLRC2 protein; NKG2C_HUMAN.   
规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 肿瘤  细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Monkey, 
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=5μg /test IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 26kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NKG2C:51-150/231 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Natural killer (NK) cells are lymphocytes that can mediate the lysis of certain tumor cells and virus infected cells without being previously activated. They can also regulate specific humoral and cell mediated immunity. NK cells preferentially express several calcium dependent (C type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C type lectin genes preferentially expressed on NK cells.

Function:
Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.

Subunit:
Can form disulfide-bonded heterodimer with CD94. Interacts with TYROBP.

Subcellular Location:
Membrane; Single-pass type II membrane protein.

Tissue Specificity:
Natural killer cells.

Similarity:
Contains 1 C-type lectin domain.

SWISS:
P26717

Gene ID:
3822

Database links:

Entrez Gene: 3822 Human

Omim: 602891 Human

SwissProt: P26717 Human

Unigene: 591157 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

自然杀伤细胞活化性受体2C
产品图片
Image kindly submitted by Shoko Hagen at Oregon Health and Science University. Rhesus Macaques PBMCs were stained with 5uL per tube of Rabbit Anti-NKG2C Polyclonal Antibody, FITC Conjugated (bs-2416R-FITC)