Anti-CD58/LFA3抗体-抗体-抗体-生物在线
Anti-CD58/LFA3抗体

Anti-CD58/LFA3抗体

商家询价

产品名称: Anti-CD58/LFA3抗体

英文名称: CD58/LFA3

产品编号: YB--2498R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
  • 联系人 : 陈环环
  • 地址 : 上海市沪闵路6088号龙之梦大厦8楼806室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 183****2235
  • 传真 : 021-60514606
  • 邮箱 : shybio@126.com

 Anti-CD58/LFA3抗体

产品编号 YB-2498R
英文名称 CD58/LFA3
中文名称 淋巴细胞功能相关抗原-3抗体
别    名 LFA-3; AG3; Ag3; CD58; CD58 antigen (lymphocyte function associated antigen 3)1; CD58 antigen; CD58 antigen, (lymphocyte function associated antigen 3); CD58 molecule; FLJ23181; FLJ43722; LFA 3; LFA3; LFA3_HUMAN; Lymphocyte Function Associated Antigen Type 3; Lymphocyte function-associated antigen 3; Surface glycoprotein LFA 3; Surface glycoprotein LFA-3.  
规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD58:31-130/250 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
LFA3 is a type 1 transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed on most hematopoietic cells and on nonhematopoietic cells such as fibroblasts, endothelial and epithelial cells. Its expression is particularly high on memory T-cells and dendritic cells. LFA3 expression on antigen-presenting cells and target cells enhances T-cells antigen recognition through binding to its ligand, LFA2/CD2, on T-cells.

Function:
Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.

Subcellular Location:
Isoform 1: Cell membrane; Single-pass type I membrane protein. 
Isoform 2: Cell membrane; Lipid-anchor, GPI-anchor. 

Similarity:
Contains 1 Ig-like C2-type (immunoglobulin-like) domain. 

SWISS:
P19256

Gene ID:
965

Database links:

Entrez Gene: 965 Human

Omim: 153420 Human

SwissProt: P19256 Human

Unigene: 34341 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
 
产品图片
Sample: Raji Cell lysate at 30ug; 
Primary: Anti-CD58/LFA3 (bs-2498R) at 1:300 dilution; 
Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000 dilution; 
Predicted band size: 25 kD
Observed band size: 50 kD