FITC标记的同源转录因子DLX2抗体
产品名称： FITC标记的同源转录因子DLX2抗体
英文名称： Anti-DLX2/FITC
产品编号： HZ-20452R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-DLX2/FITC Conjugated antibody
FITC标记的同源转录因子DLX2抗体
| 英文名称 | Anti-DLX2/FITC |
| 中文名称 | FITC标记的同源转录因子DLX2抗体 |
| 别 名 | DII A; Distal less homeo box 2; Distal less homeobox 2; Distal-less homeobox 2; DLX 2; Dlx2; DLX2_HUMAN; Dlx5; Homeobox protein DLX 2; Homeobox protein DLX-2; Homeobox protein DLX2; Homeobox protein TES 1; Homeobox protein TES-1; Homeobox protein TES1; Tes 1; Tes-1; Tes1; zgc. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 信号转导 干细胞 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 34kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 2mg/1ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DLX2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Dlx genes are a highly conserved family of six different (Dlx1–6) homeo box-containing genes that share homology with distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. Dlx genes are expressed in spatially and temporally restricted patterns in craniofacial primordia, basal telencephalon and diencephalon, and in distal regions of extending appendages, including the limb and the genital bud. The differential expression of Dlx influences patterning, morphogenesis and histogenesis in these tissues. The Dlx gene products can activate transcription and are localized primarily to the nucleus, although Dlx-5 can be found in the cytoplasm. Dlx proteins influence different stages of proper tissue development, including patterning of the orofacial skeleton (craniofacial ectomesenchyme) and differentiation of structures within and between teeth. Function: Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis. Subcellular Location: Nucleus. Similarity: Belongs to the distal-less homeobox family. Contains 1 homeobox DNA-binding domain. Database links: Entrez Gene: 1746 Human Entrez Gene: 13392 Mouse Omim: 126255 Human SwissProt: Q07687 Human SwissProt: P40764 Mouse Unigene: 419 Human Unigene: 3896 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
Dlx基因是一个高度保守的家族，由六个不同的（Dlx1-6）含同源盒的基因组成，与发育中的果蝇头部和四肢中表达的无远端（Dll）基因具有同源性。Dlx基因在颅面部原基、基底端脑和间脑以及延伸附件的远端区域，包括肢体和生殖芽中，以空间和时间限制的方式表达。Dlx的差异表达影响这些组织的模式、形态发生和组织发生。Dlx基因产物可以激活转录，并且主要定位于细胞核，尽管在细胞质中可以找到Dlx-5。Dlx蛋白影响正常组织发育的不同阶段，包括口面部骨骼（颅面部外胚间充质细胞）的图案化和牙齿内部和之间的结构分化。