FITC标记的GTP发育调控结合蛋白1抗体上海沪震实业有限公司

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产品名称: FITC标记的GTP发育调控结合蛋白1抗体
英文名称: Anti-DRG1/FITC
抗体货号: HZ-20290R-FITC
产品规格: 100ul
级    别: , , 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/12/5 15:17:00
详细资料:  实验方法技术资料
浏览人数:4
诚信指数:1084点
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
地址:
上海市杨浦区密云路1018号复旦科技园808室
邮编:
200612
电话:
021-60345367
传真:
021-31320307
联系人:
陈先生
所在区域:
上海·中国-上海
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产品详细描述

 Rabbit Anti-DRG1/FITC Conjugated antibody

FITC标记的GTP发育调控结合蛋白1抗体

 

英文名称 Anti-DRG1/FITC
中文名称 FITC标记的GTP发育调控结合蛋白1抗体
别    名 Developmentally regulated GTP binding protein 1; Developmentally-regulated GTP-binding protein 1; DRG 1; DRG-1; DRG1; DRG1_HUMAN; NEDD 3; NEDD-3; NEDD3; Neural precursor cell expressed developmentally down regulated protein 3; Neural precursor cell expressed developmentally down-regulated protein 3.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  发育生物学  信号转导  细胞周期蛋白  转录调节因子  G蛋白信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应  
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
性    状 Lyophilized or Liquid
浓    度 2mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DRG1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
May play a role in cell proliferation, differentiation and death.High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes. 

Function:
Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest.

Subunit:
Interacts (via its C-terminal) with TAL1. Interacts with ZC3H15; the interaction forms a polysomal DRG1-DFRP1/ZC3H15 complex which provides protein stability to DRG1 possibly by blocking poly-ubiquitination. Interacts with STK16; the interaction phosphorylates STK16 

Subcellular Location:
Cytoplasm. Note=The DRG1-DFRP2/ZC3H15 complex associates with polysomes.

Tissue Specificity:
High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes.

Post-translational modifications:
Sumoylated by UBE2I in response to MEKK1-mediated stimuli. 

Similarity:
Belongs to the GTP1/OBG family. 
Contains 1 G (guanine nucleotide-binding) domain. 

Database links:

Entrez Gene: 4733 Human

Entrez Gene: 13494 Mouse

Entrez Gene: 305470 Rat

Omim: 603952 Human

SwissProt: Q9Y295 Human

SwissProt: P32233 Mouse

SwissProt: Q5I0F0 Rat

Unigene: 115242 Human

Unigene: 3250 Mouse

Unigene: 102143 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

可能在细胞增殖、分化和死亡中起作用。骨骼肌、心脏和肾脏的高水平。肝脏、胎盘和脑的中间水平。结肠、胸腺、脾脏、小肠、肺和白细胞低水平。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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