Anti-RFIP3抗体上海钰博生物科技有限公司

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产品名称: Anti-RFIP3抗体
英文名称: RFIP3
抗体货号: YB--
产品规格: 20ul/50ul/100ul/200ul
级    别: 分析纯, 见说明书
产品产地: 中国/美国
品牌商标: Ybscience
价    格: 1380元
抗原: KLH conjugated synthetic peptide derived from human FIP3:651-756/756
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: Human, Mouse, Rat,
见说明书conjugate:见说明书
Isotype:见说明书
应用范围: 科研使用
更新时间: 2018/12/6 13:16:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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产品详细描述

 Anti-RFIP3抗体

产品编号 YB-16089R
英文名称 RFIP3
中文名称 Rab11-FIP3蛋白抗体
别    名 EF hands containing Rab interacting protein; Eferin; RFIP3_HUMAN; Rab11 family interacting protein 3; RAB11FIP3; RFIP3.  
规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  免疫学  信号转导  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 WB=1:500-2000 ELISA=1:500-1000  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 82kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FIP3:651-756/756 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Mar 2008]

Function:
FIP3 (RAB11FIP3) is one of many proteins that interact with and regulate Rab GTPases. Forms an heterooligomeric complex with RAB11FIP4. Binds to RAB11A, RAB11B and RAB25.

Subunit:
Homodimer. Forms a complex with Rab11 (RAB11A or RAB11B) and ARF6. Interacts with RAB11A; the interaction is direct. Interacts with RAB11B, RAB25 and RAB11FIP4. Interacts with ARF6; according to PubMed:16148947, it specifically interacts with ARF6 but not ARF5. Interacts with ARF6; according to PubMed:17030804 but not PubMed:16148947. Interacts with RACGAP1/MgcRacGAP; interaction takes place during late stage of cytokinesis and is required for recruitment to the midbody. Interacts with ASAP1 and EXOC7.

Subcellular Location:
Recycling endosome membrane; Peripheral membrane protein. Cytoplasm; cytoskeleton; centrosome. Cleavage furrow. Midbody.

Post-translational modifications:
Phosphorylated at Ser-102 by CDK1 during metaphase, and dephosphorylated as cells enter telophase.

Similarity:
Contains 2 EF-hand domains. 
Contains 1 FIP-RBD domain. 

SWISS:
O75154 

Gene ID:
9727

Database links:

Entrez Gene: 9727 Human

Entrez Gene: 303002 Rat

Omim: 608738 Human

SwissProt: O75154 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
 
产品图片
Sample: 
U937(Human) Cell Lysate at 30 ug
Primary: Anti-RFIP3 (bs-16089R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 82 kD
Observed band size: 82 kD

   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   

 

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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