|别 名||C17orf25; CGI 150; Glod4; GLOD4_HUMAN; Glyoxalase domain containing 4; glyoxalase domain containing protein 4; Glyoxalase domain-containing protein 4; HC71; my027.|
|规格价格||100ul/1380元 购买 200ul/2200元 购买 大包装/询价|
|说 明 书||100ul 200ul|
|研究领域||肿瘤 细胞生物 免疫学 信号转导|
|交叉反应||Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,|
|产品应用||ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
|分 子 量||35kDa|
|性 状||Lyophilized or Liquid|
|免 疫 原||KLH conjugated synthetic peptide derived from human GLOD4:101-200/313|
|纯化方法||affinity purified by Protein A|
|储 存 液||0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.|
|保存条件||Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.|
GLOD4 is a 313 amino acid protein belonging to the glyoxalase I family. GLOD4 interacts with NUDT9, a highly specific adenosine diphosphate ribose pyrophosphatase. Localized to mitochondrion, GLOD4 is expressed in heart, brain, liver, kidney, pancreas and placenta, but is not found in skeletal muscle or lung. Expression of GLOD4 is decreased in hepatocellular carcinoma samples in comparison to adjacent non-cancerous liver tissues from the same patients. Transfection of GLOD4 in hepatocellular carcinoma cells and overexpression has also been shown to inhibit cell growth. GLOD4 exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 17p13.3.
Expressed in heart, brain, liver, kidney, pancreas and placenta. Not expressed in skeletal muscle and lung.
Belongs to the glyoxalase I family.
Entrez Gene: 51031 Human
Entrez Gene: 67201 Mouse
Entrez Gene: 363644 Rat
SwissProt: Q9HC38 Human
SwissProt: Q9CPV4 Mouse
SwissProt: Q5I0D1 Rat
Unigene: 279061 Human
Unigene: 595572 Human
Unigene: 482113 Mouse
Unigene: 24630 Rat
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.