FITC标记的RNA结合蛋白19抗体上海沪震实业有限公司

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产品名称: FITC标记的RNA结合蛋白19抗体
英文名称: Anti-RBM19/FITC
抗体货号: HZ-21291R-FITC
产品规格: 100ul
级    别: , , 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/12/6 15:28:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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产品详细描述

 Rabbit Anti-RBM19/FITC Conjugated antibody

FITC标记的RNA结合蛋白19抗体

 

英文名称 Anti-RBM19/FITC
中文名称 FITC标记的RNA结合蛋白19抗体
别    名 1200009A02Rik; AV302714; NPO; Probable RNA-binding protein 19; RBM19; RBM19_HUMAN; RNA-binding motif protein 19.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 信号转导  转录调节因子  结合蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 108kDa
性    状 Lyophilized or Liquid
浓    度 2mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human RBM19
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a nucleolar protein that contains six RNA-binding motifs. The encoded protein may be involved in regulating ribosome biogenesis. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Apr 2009]

Function:
Plays a role in embryo pre-implantation development.

Subcellular Location:
Nucleus > nucleolus. Nucleus > nucleoplasm. Cytoplasm. Chromosome. In discrete foci distributed throughout the cytoplasm and nucleoplasm during the 4 to 8 cell stages and the morula stage, but not in the periphery of the nucleolar precursor body (NPB). During blastocyst development, becomes increasingly localized to the nucleolus and less to the cytoplasm. At the late blastocyst stage, localized predominantly in the nucleolus. Localized in the nucleolus during interphase and to the perichromosomal sheath during mitosis. Does not colocalize in the cytoplasm with GW182 in P-bodies. May translocate to the nucleolus upon early embryonic development (By similarity). Colocalizes with NPM1 during interphase. By late prophase, metaphase, anaphase and telophase, associates with the chromosome periphery. By telophase localizes to NPB.

Tissue Specificity:
Expressed in the crypts of Lieberkuhn of the intestine and in intestinal neoplasia (at protein level).

Similarity:
Belongs to the RRM MRD1 family.
Contains 6 RRM (RNA recognition motif) domains.

Database links:

Entrez Gene: 9904 Human

Entrez Gene: 74111 Mouse

Entrez Gene: 304512 Rat

SwissProt: Q9Y4C8 Human

SwissProt: Q8R3C6 Mouse

Unigene: 7482 Human



Important Note:
   

该基因编码含有六个RNA结合基序的核仁蛋白。编码的蛋白质可能参与调节核糖体的生物合成。已经鉴定出编码相同蛋白的多个选择性剪接变异体。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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