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Anti-IGSF10抗体

Anti-IGSF10抗体

商家询价

产品名称: Anti-IGSF10抗体

英文名称: IGSF10

产品编号: YB--9200R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
  • 联系人 : 陈环环
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  • 邮编 : 200612
  • 所在区域 : 上海
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  • 邮箱 : shybio@126.com

 Anti-IGSF10抗体

产品编号 YB-9200R
英文名称 IGSF10
中文名称 免疫球蛋白超家族成员10抗体
别    名 Adlican2; Calvaria mechanical force protein 608; CMF608; IGS10_HUMAN; IgSF10; Immunoglobulin superfamily member 10.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 肿瘤  细胞生物  信号转导  细胞周期蛋白  细胞表面分子  细胞分化  细胞骨架  细胞外基质  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 288kDa
细胞定位 分泌型蛋白 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IGSF10:2001-1200/2623 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Ig (immunoglobulin) superfamily members exhibit functional characteristics including immune responses, growth factor signaling and cell adhesion. IGSF10 (immunoglobulin superfamily, member 10), also known as Calvaria mechanical force protein 608 (CMF608), is a 2,623 amino acid secreted protein that contains an N-terminal signal peptide, six leucine-rich repeats (LRRs), and 12 immunoglobulin-like repeats. IGSF10 exists as multiple alternatively spliced isoforms, and is expressed in bone. Specifically, expression of IGSF10 is limited to mesenchymal osteochondroprogenitors with fibroblast-like morphology, where it is thought to be involved in the maintenance of the osteochondroprogenitor cells pool and its down-regulation precedes terminal differentiation. The gene encoding IGSF10 maps to chromosome 3, which comprises over 1,100 genes that include a chemokine receptor gene cluster as well as a variety of human cancer related loci.

Function:
May be involved in the maintenance of osteochondroprogenitor cells pool (By similarity). 

Subcellular Location:
Secreted

Similarity:
Contains 12 Ig-like C2-type (immunoglobulin-like) domains. 
Contains 6 LRR (leucine-rich) repeats. 
Contains 1 LRRCT domain. 
Contains 1 LRRNT domain.

SWISS:
Q6WRI0

Gene ID:
285313

Database links:

Entrez Gene: 285313 Human

SwissProt: Q6WRI0 Human

Unigene: 58561 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.