Anti-ERK1/2 Polyclonal Antibody北京索莱宝科技有限公司

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产品名称: Anti-ERK1/2 Polyclonal Antibody
英文名称: Anti-ERK1/2 Polyclonal Antibody
抗体货号: K106589P
产品规格: 50ul/100ul
级    别: ,
产品产地: 北京
品牌商标: Solarbio
价    格: 960/50ul\1600/100ul元
抗原: 现做
抗原来源: 
抗体来源: 
适用物种: 
应用范围: 
更新时间: 2019/7/11 13:18:00
详细资料:  实验方法技术资料
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诚信指数:1247点
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使用范围:仅限科研使用,不能应用于临床
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北京索莱宝科技有限公司
地址:
北京市通州区马驹桥镇联东U谷景盛南四街15号85A三层
邮编:
101102
电话:
18435223305
传真:
010-56371281
联系人:
郭倩
所在区域:
北京·北京
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公司展台:
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产品详细描述



Anti-ERK1/2 Polyclonal Antibody

品牌:solarbio | 货号:K106589P
商品货号:商品品牌:规格基本售价:选择规格
K106589P-50ulsolarbio50ul960.00元
K106589P-100ulsolarbio100ul1600.00元
英文名称Anti-ERK1/2 Polyclonal Antibody
别名ERK;ERK-2;MAPK2;p38;p40;p41;p41mapk;p42-MAPK;P42MAPK;PRKM1;PRKM2
应用WB
稀释比例WB 1:500-2000.
交叉反应Human Mouse Rat
蛋白分子量41kDa
Gene ID5594
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human ERK1/2
性状液体
Public Immunogen RangeRecombinant protein of human ERK1/2
Subcellular LocationsCytoplasm Nucleus Cell membrane Cytoskeleton
Swiss ProtP28482
克隆类型Polyclonal Antibody
背景资料Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors. About 160 substrates have already been discovered for ERKs. Many of these substrates are localized in the nucleus, and seem to participate in the regulation of transcription upon stimulation.






 

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