Anti-NHLH2/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-NHLH2/FITC Conjugated抗体

Anti-NHLH2/FITC Conjugated抗体

商家询价

产品名称: Anti-NHLH2/FITC Conjugated抗体

英文名称: Anti-NHLH2/FITC

产品编号: YB--11524R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
  • 联系人 : 陈环环
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  • 邮编 : 200612
  • 所在区域 : 上海
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  • 邮箱 : shybio@126.com

 Anti-NHLH2/FITC Conjugated抗体

产品编号 YB-11524R-FITC
英文名称 Anti-NHLH2/FITC
中文名称 FITC标记的螺旋环螺旋蛋白2抗体
别    名 HEN2; Nescient helix loop helix 2; NSCL; NSCL2; HEN2_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  神经生物学  信号转导  转录调节因子  G蛋白偶联受体  表观遗传学  G蛋白信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 15kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NHLH2 (1-50aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The helix-loop-helix (HLH) structures are known motifs commonly found in membrane-active and DNA-binding proteins. The helix-loop-helix proteins HEN1 and HEN2 are DNA-binding proteins that may be involved in cell-type determination in the early nervous system. Studies of expression in normal tissues have demonstrated expression of NHLH1/NSCL-1 and NHLH2/NSCL-2, the genes encoding HEN1 and HEN2, in the developing central and peripheral nervous system, specifically in developing neurons.

Function:
NHLH2 are two basic domain helix-loop-helix (bHLH) proteins expressed predominantly in the developing nervous system and also in some cell lines derived from tumors with neural or neuroendocrine features such as neuroblastoma, PNET, and small cell lung cancer. 

Subunit:
Efficient DNA binding requires dimerization with another bHLH protein. 

Subcellular Location:
Nucleus

Similarity:
Contains 1 bHLH (basic helix-loop-helix) domain. 

Database links:
UniProtKB/Swiss-Prot: Q02577.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications