Anti-Somatostatin Receptor 2/FITC Conjugated抗体上海钰博生物科技有限公司

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产品名称: Anti-Somatostatin Receptor 2/FITC Conjugated抗体
英文名称: Anti-Somatostatin Receptor 2/FITC
抗体货号: YB--1138R-FITC
产品规格: 20ul/50ul/100ul/200ul
级    别: , 分析纯, 见说明书
产品产地: 中国/美国
品牌商标: Ybscience
价    格: 2980元
抗原: KLH conjugated synthetic peptide derived from human SSTR2
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig,
见说明书conjugate:见说明书
Isotype:见说明书
应用范围: 科研使用
更新时间: 2019/6/27 14:19:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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产品详细描述

 Anti-Somatostatin Receptor 2/FITC Conjugated抗体

产品编号 YB-1138R-FITC
英文名称 Anti-Somatostatin Receptor 2/FITC
中文名称 FITC标记的生长抑素受体2抗体
别    名 somatostatin receptor 2; Somatostatin receptor type 2; SRIF1; SS2R; SST2; SSTR2; SRIF-1; SS-2-R; SS2-R; SSR2_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  发育生物学  神经生物学  细胞凋亡  G蛋白偶联受体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, 
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SSTR2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Somatostatin is a tetradecapeptide that is widely distributed in the body and is one of five receptor subtypes termed SSTr1-. These receptors function in the regulation of numerous phsiological processes such as the secretion of insulin, glucagon and growth hormone as wel as cell growth induced by neuronal excitation in both the central and peripheral nervous systems. Somatostatin receptos are activated via sonatostatin secreted by nerve and endocrine cells. Somatostatin Receptor 2 (SSR2), along with SSR1, is expressed at the highest levels in the stomach and jejunum, cerebrum and kidney, respectively.

Function:
Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels.

Subunit:
The C-terminus interacts with SHANK1 PDZ domain.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Cerebrum and kidney. In lesser amounts in jejunum, colon and liver.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 6752 Human

Entrez Gene: 20606 Mouse

Entrez Gene: 54305 Rat

Omim: 182452 Human

SwissProt: P30874 Human

SwissProt: P30875 Mouse

SwissProt: P30680 Rat

Unigene: 514451 Human

Unigene: 454968 Mouse

Unigene: 202974 Rat

Unigene: 9929 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

SSTR2的表达在肿瘤的分布、发生和发展中起重要作用。目前主要用于肿瘤方面的研究

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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