Anti-Stanniocalcin 2/FITC Conjugated抗体
产品名称: Anti-Stanniocalcin 2/FITC Conjugated抗体
英文名称: Anti-Stanniocalcin 2/FITC
产品编号: YB--12379R-FITC
产品价格: null
产品产地: 中国/美国
品牌商标: Ybscience
更新时间: 2023-08-17T10:29:50
使用范围: 科研使用
上海钰博生物科技有限公司
- 联系人 : 陈环环
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- 邮编 : 200612
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Anti-Stanniocalcin 2/FITC Conjugated抗体
产品编号 | YB-12379R-FITC |
英文名称 | Anti-Stanniocalcin 2/FITC |
中文名称 | FITC标记的斯钙素2抗体 |
别 名 | Stanniocalcin related protein; Stanniocalcin-2; Stanniocalcin-related protein; Stanniocalcin2; STC 2; STC related protein; STC-2; STC-related protein; STC2; STC2_HUMAN; STCRP. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 发育生物学 信号转导 干细胞 糖蛋白 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 31kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Stanniocalcin 2 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Stanniocalcin 1 (STC1) and stanniocalcin 2 (STC2) are mammalian peptide hormones that were previously considered to be present only in bony fish, where they are involved in calcium homeostasis. STC1 plays a role in calcium and phosphate homoeostasis and is phosphorylated in vitro by protein kinase C, and STC2 is phosphorylated in vitro by casein kinase II (CK2). A human fibrosarcoma cell line, HT1080, expresses both STC1 and STC2 as secreted phosphoproteins in vivo, with STC2 being phosphorylated by an ecto-CK2-like enzyme. STC1 and STC2 have opposite effects on calcium and phosphate homeostasis, namely anti-hypercalcemic and anti-hypocalcemic actions, respectively. STC1 and STC2 are detected in human adrenal tumors, such as pheochromocytoma, differentiated neuroblastoma aldosterone-producing adenoma, and in cultured adrenal tumor cells (rat pheochromocytoma PC-12 cells and human neuroblastoma NB-1 cells). Function: Has an anti-hypocalcemic action on calcium and phosphate homeostasis. Subcellular Location: Secreted. Tissue Specificity: Expressed in a variety of tissues including muscle, heart, pancreas, kidney, spleen, prostate, small intestine, colon and peripheral blood leukocytes. Similarity: Belongs to the stanniocalcin family. Database links: Entrez Gene: 540573 Cow Entrez Gene: 8614 Human Entrez Gene: 20856 Mouse Entrez Gene: 100126236 Pig Entrez Gene: 63878 Rat Entrez Gene: 548758 Xenopus tropicalis Omim: 603665 Human SwissProt: O76061 Human SwissProt: O88452 Mouse SwissProt: Q9R0K8 Rat Unigene: 233160 Human Unigene: 32506 Mouse Unigene: 44823 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |