Anti-TCL3/HOX11/FITC Conjugated抗体
产品名称： Anti-TCL3/HOX11/FITC Conjugated抗体
英文名称： Anti-TCL3/HOX11/FITC
产品编号： YB--17360R-FITC
产品价格： null
产品产地： 中国/美国
品牌商标： Ybscience
更新时间： 2023-08-17T10:29:50
使用范围： 科研使用
上海钰博生物科技有限公司
- 联系人 : 陈环环
- 地址 : 上海市沪闵路6088号龙之梦大厦8楼806室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 183****2235
- 传真 : 021-60514606
- 邮箱 : shybio@126.com
Anti-TCL3/HOX11/FITC Conjugated抗体
| 产品编号 | YB-17360R-FITC |
| 英文名称 | Anti-TCL3/HOX11/FITC |
| 中文名称 | FITC标记的T细胞白血病淋巴瘤蛋白3抗体 |
| 别 名 | Homeo box 11 (T cell leukemia 3 associated breakpoint homologous to Drosophila Notch); Homeo box 11 (T cell lymphoma 3 associated breakpoint); Homeobox 11; Homeobox protein Hox 11; Homeobox protein Hox-11; Homeobox TLX-1; Hox-11; Hox11; MGC163402; OTTHUMP00000020816; Proto oncogene TCL 3; Proto-oncogene TCL-3; RGD1563655; T cell leukemia homeobox protein 1; T cell leukemia lymphoma protein 3; T-all, included; T-cell acute lymphocytic leukemia, included; T-cell leukemia 3 gene; T-cell leukemia homeobox protein 1; T-cell leukemia, homeobox 1; T-cell leukemia/lymphoma protein 3; TCL 3 proto oncogene; TCL3; Tlx-1; TLX1; TLX1_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 发育生物学 转录调节因子 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 34kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TCL3/HOX11 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. The Hox11 gene, termed an orphan homeobox gene, as it is located outside of the four mammalian Hox clusters, is a DNA-binding nuclear transcription factor. The human Hox11 gene maps to chromosome 10q24 and has been implicated in the chromosomal translocation t(7;10)(q24;q11) that occurs in T-cell acute lymphoblastic leukemia (T-ALL). The t(7:10) translocation occurs between the Hox11 gene and the T-cell receptor (TCR) delta-chain gene and is a result of aberrant physiological recombinational events at the early stages of T-cell development. The Hox11 gene is normally expressed in the splanchnic anlage arising from the splanchnic mesoderm. Homozygous Hox11-deficient mice have no spleen, while all other splanchnic derivatives develop normally. Spleen development starts and proceeds normally in Hox11-deficient mice to a specific stage of embryogenesis, when the spleen anlage becomes fully absorbed. Function: Controls the genesis of the spleen. Binds to the DNA sequence 5'-GGCGGTAAGTGG-3'. Subcellular Location: Nucleus. DISEASE: Note=A chromosomal aberration involving TLX1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(10;14)(q24;q11) with TCRD. Similarity: Contains 1 homeobox DNA-binding domain. Database links: Entrez Gene: 3195 Human Entrez Gene: 21908 Mouse Entrez Gene: 499361 Rat Omim: 186770 Human SwissProt: P31314 Human SwissProt: P43345 Mouse SwissProt: D4A270 Rat Unigene: 89583 Human Unigene: 391203 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applicationS |