Anti-MARVELD2/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-MARVELD2/FITC Conjugated抗体

Anti-MARVELD2/FITC Conjugated抗体

商家询价

产品名称: Anti-MARVELD2/FITC Conjugated抗体

英文名称: Anti-MARVELD2/FITC

产品编号: YB--18684R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-MARVELD2/FITC Conjugated抗体

产品编号 YB-18684R-FITC
英文名称 Anti-MARVELD2/FITC
中文名称 FITC标记的MARVEL蛋白家族D2抗体
别    名 DFNB49; FLJ30532; MARVD2; MARVEL (membrane associating) domain containing 2; MARVEL domain containing 2; MARVEL domain containing protein 2; MARVELD 2; MARVELD2; MRVLDC2; Tric; Tricellulin.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Monkey, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Bat
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 64kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MARVELD2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene is a membrane protein found at the tight junctions between epithelial cells. The encoded protein helps establish epithelial barriers such as those in the organ of Corti, where these barriers are required for normal hearing. Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Function:
Plays a role in the formation of the epithelial barriers. The separation of the endolymphatic and perilymphatic spaces of the organ of Corti from one another by epithelial barriers is required for normal hearing. 

Subcellular Location:
Cell membrane; Multi-pass membrane protein. Cell junction, tight junction. Note=Found at tricellular contacts. 

DISEASE:
Deafness, autosomal recessive, 49 (DFNB49) [MIM:610153]: A form of non-syndromic sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. Note: The disease is caused by mutations affecting the gene represented in this entry. 

Similarity:
Contains 1 MARVEL domain.

Database links:

Entrez Gene: 461831 Chimpanzee

Entrez Gene: 101128096 Gorilla

Entrez Gene: 153562 Human

Entrez Gene: 100173144 Orangutan

Entrez Gene: 100516404 Pig

Entrez Gene: 365657 Rat

Omim: 610572 Human

SwissProt: Q8N4S9 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications