Anti-Neurochondrin/FITC Conjugated抗体上海钰博生物科技有限公司

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产品名称: Anti-Neurochondrin/FITC Conjugated抗体
英文名称: Anti-Neurochondrin/FITC
抗体货号: YB--19517R-FITC
产品规格: 20ul/50ul/100ul/200ul
级    别: , 分析纯, 见说明书
产品产地: 中国/美国
品牌商标: Ybscience
价    格: 2980元
抗原: KLH conjugated synthetic peptide derived from human Neurochondrin
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: Human,
见说明书conjugate:见说明书
Isotype:见说明书
应用范围: 科研使用
更新时间: 2019/7/11 11:45:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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产品详细描述

 Anti-Neurochondrin/FITC Conjugated抗体

产品编号 YB-19517R-FITC
英文名称 Anti-Neurochondrin/FITC
中文名称 FITC标记的神经软骨蛋白NCDN1抗体
别    名 AU042419; KIAA0607; M-Sema F-associating protein of 75 kDa; MGC93259; MMS10-AE; Ms10ae; NCDN; NCDN-1; Neurochondrin 1; Norbin; OTTHUMP00000065369; OTTHUMP00000065370; OTTHUMP00000065371; Sfap75.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  神经生物学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 79kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Neurochondrin
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a leucine-rich cytoplasmic protein, which is highly similar to a mouse protein that negatively regulates Ca/calmodulin-dependent protein kinase II phosphorylation and may be essential for spatial learning processes. Several alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jul 2008]

Function:
Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling By similarity. Required for the spatial learning process. Acts as a negative regulator of Ca2+-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin-concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth.

Subcellular Location:
Cytoplasm. Cell projection, dendrite.

Tissue Specificity:
Abundantly expressed in whole adult brain and in all individual brain regions examined, including spinal cord. Weakly expressed in ovary, testis, fetal brain and small intestine.

Similarity:
Interacts with SEMA4C, DIAPH1 (via FH3 domain) and GRM5 By similarity. Interacts with MCHR1.

Database links:

Entrez Gene: 23154 Human

Entrez Gene: 505994 Cow

Entrez Gene: 26562 Mouse

Entrez Gene: 89791 Rat

Omim: 608458 Human

SwissProt: Q2KJ97 Cow

SwissProt: Q9UBB6 Human

SwissProt: Q91YH7 Mouse

SwissProt: O35095 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

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