Anti-PDE1A/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-PDE1A/FITC Conjugated抗体

Anti-PDE1A/FITC Conjugated抗体

商家询价

产品名称: Anti-PDE1A/FITC Conjugated抗体

英文名称: Anti-PDE1A/FITC

产品编号: YB--9967R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-PDE1A/FITC Conjugated抗体

产品编号 YB-9967R-FITC
英文名称 Anti-PDE1A/FITC
中文名称 FITC标记的磷酸二酯酶1A抗体
别    名 3' 5' cyclic nucleotide phosphodiesterase; 5''-cyclic nucleotide phosphodiesterase 1A; 61 kDa Cam PDE; 61 kDa Cam-PDE; Calcium/calmodulin dependent 3' 5' cyclic nucleotide phosphodiesterase 1A; Calcium/Calmodulin stimulated cyclic nucleotide phosphodiesterase; Calcium/calmodulin-dependent 3''; Calmodulin-dependent Phosphodiesterase; Cam PDE 1A; Cam-PDE 1A; CAM-PDE-1A; HCAM 1; hCam-1; HCAM1; HSPDE1A; MGC26303; PDE 1A; PDE1A; PDE1A_HUMAN; Phosphodiesterase 1A; Phosphodiesterase 1A calmodulin dependent.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 61kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PDE1A
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM, Oct 2009]

Function:
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP.

Tissue Specificity:
Several tissues, including brain, kidney, testes and heart.

Similarity:
Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.

Database links:

Entrez Gene: 281969 Cow

Entrez Gene: 403652 Dog

Entrez Gene: 5136 Human

Entrez Gene: 18573 Mouse

Entrez Gene: 81529 Rat

GenBank: NP_005010.2 Human

Omim: 171890 Human

SwissProt: P14100 Cow

SwissProt: P54750 Human

SwissProt: Q61481 Mouse

Unigene: 191046 Human

Unigene: 680373 Human

Unigene: 40678 Mouse

Unigene: 204552 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications