Anti-PDLIM5/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-PDLIM5/FITC Conjugated抗体

Anti-PDLIM5/FITC Conjugated抗体

商家询价

产品名称: Anti-PDLIM5/FITC Conjugated抗体

英文名称: Anti-PDLIM5/FITC

产品编号: YB--12601R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
  • 联系人 : 陈环环
  • 地址 : 上海市沪闵路6088号龙之梦大厦8楼806室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 183****2235
  • 传真 : 021-60514606
  • 邮箱 : shybio@126.com

 Anti-PDLIM5/FITC Conjugated抗体

产品编号 YB-12601R-FITC
英文名称 Anti-PDLIM5/FITC
中文名称 FITC标记的PDZ和LIM结构域结合蛋白5抗体
别    名 ENH; ENH1; Enigma homolog; Enigma like LIM domain protein; Enigma like PDZ and LIM domains protein; Enigma-like PDZ and LIM domains protein; L 9; L9; LIM; PDLI5_HUMAN; PDLIM5; PDZ and LIM domain 5; PDZ and LIM domain protein 5.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  细胞生物  神经生物学  信号转导  转录调节因子  激酶和磷酸酶  结合蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 64kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PDLIM5
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z-disk in striated muscles. It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]

Function:
May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons. May restrain postsynaptic growth of excitatory synapses.

Subcellular Location:
Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse > synaptosome. Cytoplasm. Detected both at presynaptic and postsynaptic sites.

Tissue Specificity:
Heart and skeletal muscle specific. Expression is commonly increased in the brain of patients with bipolar disorder, schizophrenia, and major depression.

Similarity:
Contains 3 LIM zinc-binding domains.
Contains 1 PDZ (DHR) domain.

Database links:

Entrez Gene: 503621 Cow

Entrez Gene: 10611 Human

Entrez Gene: 56376 Mouse

Entrez Gene: 64353 Rat

Omim: 605904 Human

SwissProt: Q96HC4 Human

SwissProt: Q8CI51 Mouse

SwissProt: Q62920 Rat

Unigene: 480311 Human

Unigene: 117709 Mouse

Unigene: 221146 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications