Anti-SUCLA2/Renal carcinoma antigen NYREN39/FITC Conjugated抗体上海钰博生物科技有限公司

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产品名称: Anti-SUCLA2/Renal carcinoma antigen NYREN39/FITC Conjugated抗体
英文名称: Anti-SUCLA2/Renal carcinoma antigen NYREN39/FITC
抗体货号: YB--12838R-FITC
产品规格: 20ul/50ul/100ul/200ul
级    别: , 分析纯, 见说明书
产品产地: 中国/美国
品牌商标: Ybscience
价    格: 2980元
抗原: KLH conjugated synthetic peptide derived from human SUCLA2/Renal carcinoma antigen NYREN39
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Chimpanzee,
见说明书conjugate:见说明书
Isotype:见说明书
应用范围: 科研使用
更新时间: 2019/7/19 9:20:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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产品详细描述

 Anti-SUCLA2/Renal carcinoma antigen NYREN39/FITC Conjugated抗体

产品编号 YB-12838R-FITC
英文名称 Anti-SUCLA2/Renal carcinoma antigen NYREN39/FITC
中文名称 FITC标记的肾细胞癌抗原nyren39抗体
别    名 ATP specific succinyl CoA synthetase subunit beta; ATP-specific succinyl-CoA synthetase subunit beta; Renal carcinoma antigen NY-REN-39; Renal carcinoma antigen NYREN39; SCS betaA; SCS-betaA; SUCB1_HUMAN; Succinyl CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl CoA synthetase beta A chain; Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase beta-A chain; SUCLA2.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  信号转导  干细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Chimpanzee, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
性    状 Lyophilized or Liquid
浓    度 2mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SUCLA2/Renal carcinoma antigen NYREN39
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6. [provided by RefSeq, Jul 2008]

Function:
Catalyzes the ATP-dependent ligation of succinate and CoA to form succinyl-CoA.

Subcellular Location:
Mitochondrion.

Tissue Specificity:
Widely expressed.

DISEASE:
Defects in SUCLA2 are the cause of mitochondrial DNA depletion syndrome type 5 (MTDPS5) [MIM:612073]. A disorder characterized by infantile onset of hypotonia, neurologic deterioration, a hyperkinetic-dystonic movement disorder, external ophthalmoplegia, deafness, variable renal tubular dysfunction, and mild methylmalonic aciduria.

Similarity:
Belongs to the succinate/malate CoA ligase beta subunit family.
Contains 1 ATP-grasp domain.

Database links:

Entrez Gene: 8803 Human

Entrez Gene: 20916 Mouse

Entrez Gene: 361071 Rat

Omim: 603921 Human

SwissProt: Q9P2R7 Human

SwissProt: Q9Z2I9 Mouse

SwissProt: B2RZ24 Rat

Unigene: 546323 Human

Unigene: 38951 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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