Anti-ZNF238/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-ZNF238/FITC Conjugated抗体

Anti-ZNF238/FITC Conjugated抗体

商家询价

产品名称: Anti-ZNF238/FITC Conjugated抗体

英文名称: Anti-ZNF238/FITC

产品编号: YB--7195R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-ZNF238/FITC Conjugated抗体

产品编号 YB-7195R-FITC
英文名称 Anti-ZNF238/FITC
中文名称 FITC标记的锌指蛋白238抗体
别    名 58 kDa repressor protein; C2H2 171; C2H2171; RP58; TAZ 1; TAZ-1; TAZ1; Transcriptional repressor RP58; Translin associated zinc finger protein 1; Translin-associated zinc finger protein 1; ZBTB18; Zinc finger and BTB domain containing protein 18; Zinc finger and BTB domain-containing protein 18; Zinc finger protein 238; Zinc finger protein C2H2 171; Zinc finger protein C2H2-171; ZN238_HUMAN; ZNF238.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 转录调节因子  结合蛋白  锌指蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Rabbit, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 58kDa
性    状 Lyophilized or Liquid
浓    度 2mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNF238
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a C2H2-type zinc finger protein which acts a transcriptional repressor of genes involved in neuronal development. The encoded protein recognizes a specific sequence motif and recruits components of chromatin to target genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Function:
Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons (By similarity). Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a role in the organization of chromosomes in the nucleus.

Subcellular Location:
Nucleus. Associates with condensed chromatin.

Tissue Specificity:
Lymphoid tissues, testis, heart, brain, skeletal muscle, and pancreas and, at much lower level, other tissues.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Contains 1 BTB (POZ) domain. 
Contains 4 C2H2-type zinc fingers.

Database links:

Entrez Gene: 10472 Human

Entrez Gene: 30928 Mouse

Entrez Gene: 64619 Rat

Omim: 608433 Human

SwissProt: Q99592 Human

SwissProt: Q9WUK6 Mouse

SwissProt: Q9JKY3 Rat

Unigene: 69997 Human

Unigene: 207206 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications