Anti-Claudin 9/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-Claudin 9/FITC Conjugated抗体

Anti-Claudin 9/FITC Conjugated抗体

商家询价

产品名称: Anti-Claudin 9/FITC Conjugated抗体

英文名称: Anti-Claudin 9/FITC

产品编号: YB--2817R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-Claudin 9/FITC Conjugated抗体

产品编号 YB-2817R-FITC
英文名称 Anti-Claudin 9/FITC
中文名称 FITC标记的紧密连接蛋白9抗体
别    名 Claudin-9; Claudin9; CLDN9; CLD9_HUMAN  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  通道蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应  
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 23kDa
性    状 Lyophilized or Liquid
浓    度 2mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Claudin 9
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein is one of the entry cofactors for hepatitis C virus. Mouse studies revealed that this gene is required for the preservation of sensory cells in the hearing organ and the gene deficiency is associated with deafness. [provided by RefSeq, Jun 2010]

Function:
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity (By similarity). May act as a coreceptor for HCV entry into hepatic cells.

Subcellular Location:
Cell junction; Cell membrane, Multi-pass membrane protein;

Tissue Specificity:
Expressed in the liver, in peripheral blood mononuclear cells and hepatocarcinoma cell lines.

Similarity:
Belongs to the claudin family.

Database links:

Entrez Gene: 9080 Human

Entrez Gene: 56863 Mouse

Entrez Gene: 287099 Rat

Omim: 615799 Human

SwissProt: O95484 Human

SwissProt: Q9Z0S7 Mouse

Unigene: 296949 Human

Unigene: 491368 Mouse

Unigene: 113196 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications