性能参数
产品名称: Anti-HTR2C Polyclonal Antibody
英文名称: Anti-HTR2C Polyclonal Antibody
抗体货号: K108679P
产品规格:
产品产地: 北京
品牌商标: Solarbio
价 格: 询价
抗原来源:
抗体来源: Rabbit
适用物种: Human Mouse Rat
应用范围: WB
更新时间: 2021/1/15 15:13:00
详细资料:
实验方法技术资料
浏览人数:26
供应商: 北京索莱宝科技有限公司
诚信指数:1451点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。
产品详细描述
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca2+ ions from intracellular stores. Regulates neuronal activity via the activation of short transient receptor potential calcium channels in the brain, and thereby modulates the activation of pro-opiomelacortin neurons and the release of CRH that then regulates the release of corticosterone. Plays a role in the regulation of appetite and eating behavior, responses to anxiogenic stimuli and stress. Plays a role in insulin sensitivity and glucose homeostasis.
生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。
查看Anti-HTR2C Polyclonal Antibody产品的用户还对以下产品感兴趣
暂无