Anti-HTR2C Polyclonal Antibody-抗体-抗体-生物在线

Anti-HTR2C Polyclonal Antibody

商家询价

产品名称： Anti-HTR2C Polyclonal Antibody

英文名称： Anti-HTR2C Polyclonal Antibody

产品编号： K108679P

产品价格： null

产品产地：北京

品牌商标： Solarbio

更新时间： 2024-10-12T10:12:16

使用范围： WB

北京索莱宝科技有限公司

联系人 : 索莱宝-龚思雨
地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
邮编 : 101102
所在区域 : 北京
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产品详情

备注：

以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。

These protocols are for reference only. Solarbio does not independently validate these methods.

实验图

英文名称	Anti-HTR2C Polyclonal Antibody
宿主	Rabbit
别名	5-HT1C;5-HT2C;5-HTR2C;5HTR2C;HTR1C;5-hydroxytryptamine receptor 2C
稀释比例	WB 1:1000-3000.
蛋白分子量	28/51kDa
Gene ID	3358
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	A synthetic peptide of Human HTR2C
Swiss Prot	P28335
背景资料	G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca2+ ions from intracellular stores. Regulates neuronal activity via the activation of short transient receptor potential calcium channels in the brain, and thereby modulates the activation of pro-opiomelacortin neurons and the release of CRH that then regulates the release of corticosterone. Plays a role in the regulation of appetite and eating behavior, responses to anxiogenic stimuli and stress. Plays a role in insulin sensitivity and glucose homeostasis.
Public Immunogen Range	130-180/458aa
克隆类型	Polyclonal Antibody
交叉反应	Human Rat Mouse
应用	WB
规格	50ul 100ul