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Ustekinumab ( 乌司奴单抗 )福因德科技(武汉)有限公司

性能参数

产品名称: Ustekinumab ( 乌司奴单抗 )
抗体货号: FrdE00031
产品规格: 100ug
级    别: ,
产品产地: 中国
品牌商标: Frdbio
价    格: 询价
抗原来源: 
抗体来源: 
适用物种: 
应用范围: 仅供科研使用
更新时间: 2022/8/31 10:40:00
详细资料:  实验方法技术资料
浏览人数:42
诚信指数:360点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
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供应商联系卡

福因德科技(武汉)有限公司
地址:
光谷国际B座1513
邮编:
电话:
027-87877773
传真:
02787877773
联系人:
赵先生
所在区域:
湖北·武汉
邮件:
公司展台:
在线QQ:
我是2633787800,请问我有什么可以帮到您呢?

产品详细描述

Product name:Ustekinumab ( 乌司奴单抗 )

Catalog No. : FrdE00031

MW:148000.00 Da

Description:Ustekinumab is a human immunoglobulin (Ig) G1 kappa monoclonal antibody directed against interleukin(IL)-12 and IL-23, which are cytokines that are involved in immune and inflammatory responses.2 It was generated via recombinant human IL-12 immunization of human Ig (hu-Ig) transgenic mice.2 It is a targeted biologic disease-modifying anti-rheumatic drug (bDMARDs) that is used in the management of various inflammatory conditions that involve the activation of IL-12 and IL-23 signalling pathways.Interleukin (IL)-12 and IL-23 are heterodimeric cytokines that evoke immune and inflammatory responses, such as natural killer cell activation and CD4+ T-cell differentiation and activation.The role of IL-12 and IL-23 were implicated in a variety of chronic inflammatory conditions, such as psoriasis and inflammatory bowel diseases. They modulate lymphocyte function, including T-helper (Th) 1 and Th17 cell subsets,2 as CD4+ T cells can differentiate into T-helper (Th) effector lineages based on the environment. Th cells can further activate the downstream pro-inflammatory mediators and transcription factors such as TNFα and IFNγ that drive innate and adaptive immunity.

Alternative names:Ustekinumab

Specificity target name;species:IL12B[Homo sapiens]

Form: Liquid

Receptor identification:IgG1-kappa

Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 °C for frequent use. Store at -20 to -80 °C for twelve months from the date of receipt.

Purity:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Note: This product is for research use only,not for diagnostic or therapeutic use.


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