生物在线 - 让科研更便捷 :生命科学专业网,试剂,仪器,抗体,耗材在线查询

Infliximab ( 英利昔单抗 )福因德科技(武汉)有限公司

性能参数

产品名称: Infliximab ( 英利昔单抗 )
抗体货号: FrdE00026
产品规格: 100ug
级    别: ,
产品产地: 中国
品牌商标: Frdbio
价    格: 询价
抗原来源: 
抗体来源: 
适用物种: 
应用范围: 仅供科研使用
更新时间: 2022/8/31 10:43:00
详细资料:  实验方法技术资料
浏览人数:33
诚信指数:360点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
点此求购
在线QQ: 我是2633787800,请问我有什么可以帮到您呢?
生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

供应商联系卡

福因德科技(武汉)有限公司
地址:
光谷国际B座1513
邮编:
电话:
027-87877773
传真:
02787877773
联系人:
赵先生
所在区域:
湖北·武汉
邮件:
公司展台:
在线QQ:
我是2633787800,请问我有什么可以帮到您呢?

产品详细描述

Product name:Infliximab ( 英利昔单抗 )

Catalog No. : FrdE00026

MW:149000.00 Da

Description:Infliximab is a humanized antibody against tumor necrosis factor α (TNF-α) that is used in the treatment of Crohn's disease and rheumatoid arthritis.Infliximab is a IgG1κ monoclonal antibody that binds to soluble and transmembrane forms of TNF-α with high affinity to disrupt the pro-inflammatory cascade signalling.Binding of the antibody to TNF-α prevents TNF-α from interacting with its receptors.Infliximab does not neutralize TNF-β (lymphotoxin-α),a related cytokine that utilizes the same receptors as TNF-α Label.Blocked actions of TNF-α further leads to downregulation of local and systemic pro-inflammatory cytokines (i.e. IL-1, IL-6),reduction of lymphocyte and leukocyte migration to sites of inflammation, induction of apoptosis of TNF-producing cells (i.e. activated monocytes and T lymphocytes),increased levels of nuclear factor-κB inhibitor, and reduction of reduction of endothelial adhesion molecules and acute phase proteins 3. Its inhibitory actions on TNF-α was demonstrated in human fibroblasts,endothelial cells, neutrophils, B and Tlymphocytes and epithelial cells Label.Infliximab also atteunates the production of tissue degrading enzymes synthesized by synoviocytes and/or chondrocytes. According to a transgenic mice study that developed polyarthritis due to consitutive levels of human TNF-α,infliximab decreased synovitis and joint erosions in collagen-induced arthritis and allows eroded joints to heal Label.

Alternative names:Infliximab

Specificity target name;species:TNF-alpha[Homo sapiens]

Form: Liquid

Receptor identification:IgG1-kappa

Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 °C for frequent use. Store at -20 to -80 °C for twelve months from the date of receipt.

Purity:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Note: This product is for research use only,not for diagnostic or therapeutic use.

 

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

查看Infliximab ( 英利昔单抗 )产品的用户还对以下产品感兴趣

暂无

ADVERTISEMENT

找不到您所需的产品,发布求购试试?

标题:*
描述:
姓名:*
Email:*
单位:*
电话:*
地址:*
邮编:
资料: 需要 不需要
报价: 需要 不需要
报价: 需要 不需要
我已经阅读并同意生物在线的 《服务条款》《隐私政策》;我对帐户的使用及生物在线对帐户信息的披露将接受生物在线服务条款的约束并遵守中华人民共和国法律