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Tremelimumab
CAS No. : 745013-59-6
MCE 国际站:Tremelimumab
产品活性:Tremelimumab (Ticilimumab) 是一种完全人源化的单克隆抗体,对细胞毒性 T 淋巴细胞抗原 4 (CTLA-4) 具有特异性,可用于转移性黑色素瘤研究。
研究领域:Others
作用靶点:Others
In Vitro: Tremelimumab (Ticilimumab) has a higher affinity for CTLA-4-Ig than for CD28-Ig and that the antibody is specific for cynomolgus monkeys and humans.
Tremelimumab does not bind to human leukocyte FcγR and does not trigger the release of cytokines avoiding the cytokine release syndrome, but increases the IL-2 production upon stimulation with the staphylococcal enterotoxin A in a concentration-dependent manner.
Tremelimumab enhances the IL-2 production in T-cells.相关产品:Antitumor agent-67 | Catechin 7-O-β-D-glucopyranoside | Carbobenzoxyproline | ATR-IN-9 | TBTDC | Peucenin 7-O-methyl ether | 6-Hydroxy-4-methylcoumarin | Acridine Orange base | AMT-NHS | Nylidrin hydrochloride | C13-112-tri-tail | (4S)-1-Boc-4-fluoro-D-proline | D-(+)-Fucose | OVA Peptide (323-339) | Secretin (swine) | Bletilloside A | Transcriptional Intermediary Factor 2 (TIF2) (740-753) | Pep-1 (uncapped) | Aspochalasin M | Dihydrofuran-3(2H)-one | BPK-29 hydrochloride | pppApG | MEIS-IN-2 | 2′-O-Methyl-8-methyl guanosine | Altertoxin I | Lithospermoside | Acitazanolast | FLAG peptide | [Des-Tyr1]-Met-Enkephalin | α-Carotene
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Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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