Anti-Prohibitin-抗体-抗体-生物在线
Anti-Prohibitin

Anti-Prohibitin

商家询价

产品名称: Anti-Prohibitin

英文名称: Anti-Prohibitin

产品编号: 220034

产品价格: null

产品产地: 成都正能生物

品牌商标: 正能抗体

更新时间: null

使用范围: WB

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Size  100ul

Cat code  220034

Species Cross-reactivity  H, R, M

Key Application  WB

Host  Mouse

Clone Number  5H7-D5-E2

Antibody type  Monoclonal antibody

Purified method  

Isotype  IgG1

Molecular Weight  30kDa

Sensitivity  The antibody detects endogenous level of PHB protein.

Immunogen  Purified recombinant fragment of human PHB expressed in E. Coli.

UniProt Number  P35232

GeneBank ID  NM_002634.2

Subcellular location  Mitochondrion inner membrane

Formulation  Ascitic fluid containing 0.03% sodium azide.

Altername  PHB; PHB_HUMAN; PHB1; Prohibitin;

Gene_symbol  PHB1

Summary  This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3´ UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

UniPort summary Function  Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.

Application Images :  

Western blot detection of PHB antibody in C6, COS7, 3T3 and Hela cell lysates using PHB antibody (dilution 1:1000).Predicted band size:30 KDa.Observed band size:30KDa.