Cat code 300787
Species Cross-reactivity H,M,R,Mk
Key Application WB
Antibody type polyclonal antibody
Purified method Affinity purified
Molecular Weight 30kDa
Sensitivity This antibody detects endogenous levels of ANXA5 and does not cross-react with related proteins.
Immunogen Purified recombinant human ANXA5 protein fragments expressed in E.coli.
UniProt Number P08758
GeneBank ID NM_001154
Formulation Purified Rabbit polyclonal in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Altername Anchorin CII;Annexin 5;Annexin A5;Annexin V;Annexin-5;Annexin5;AnnexinA5;AnnexinV;ANX 5;ANX A5;ANX5;ANXA5;ANXA5_HUMAN;Calphobindin I;CBP I;CBP-I;Endonexin II;ENX 2;ENX2;Lipocortin V;PAP I;PAP-I;Placental anticoagulant protein 4;Placental anticoagulant protein I ;PLACENTAL PROTEIN 4;PP 4;PP4;Thromboplastin inhibitor;VAC alpha;VAC-alpha ;Vascular anticoagulant alpha;Vascular anticoagulant-alpha.
Summary The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways.Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction,inflammation,growth and differentiation.Annexin 5 has also been described as placental anticoagulant protein I,vascular anticoagulant-alpha,endonexin II,lipocortin V,placental protein 4 and anchorin CII.The gene spans 29 kb containing 13 exons,and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.[provided by RefSeq,Jul 2008]
UniPort summary Function This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex,which is involved in the blood coagulation cascade.
Application Images :
Western blot detection of ANXA5 antibody in 3T3,Hela,C6,COS7 and MCF7 cell lysates using ANXA5 antibody (1:2000 diluted).Predicted band size:30KDa.Observed band size:30KDa.Exposure time:20s.