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LRSAM1 抗体

LRSAM1 抗体

商家询价

产品名称： LRSAM1 抗体

英文名称： LRSAM1 Antibody

产品编号： XY24666-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
  • 联系人 : 徐经理
  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 152****8802
  • 传真 : 021-37680378
  • 邮箱 : shxysw02@163.com
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 LRSAM1 抗体

Applications
In-house applications ELISA, WB, IHC, IF     Application not tested? Please see our Guarantee.
Species specificity Human, Mouse; other species not tested.
Images
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  • 24666-1-AP;Jurkat cellsJurkat cells were subjected to SDS PAGE followed by western blot with 24666-1-AP( LRSAM1 Antibody) at dilution of 1:1000
  • 24666-1-AP;human skeletal muscle tissueImmunohistochemistry of paraffin-embedded human skeletal muscle slide using 24666-1-AP( LRSAM1 Antibody) at dilution of 1:50
  • 24666-1-AP;human skeletal muscle tissueImmunohistochemistry of paraffin-embedded human skeletal muscle slide using 24666-1-AP( LRSAM1 Antibody) at dilution of 1:50
  • 24666-1-AP;A431 cellsImmunofluorescent analysis of A431 cells using 24666-1-AP( LRSAM1 Antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG
Positive WB detected in Jurkat cells, HepG2 cells, mouse liver tissue
Positive IHC detected in Human skeletal muscle tissue
Positive IF detected in A431 cells
Recommended dilution WB : 1:500-1:5000
IHC : 1:20-1:200
IF : 1:10-1:100
 LRSAM1 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen LRSAM1 fusion protein ag20415 Full name Leucine rich repeat and sterile alpha motif containing 1
Calculated molecular
weight		 723aa,84 kDa Observed molecular 
weight		 84 kDa
GenBank accession 
number		 BC009239 Gene ID (NCBI) 90678
Gene symbol LRSAM1 Synonyms FLJ31641, hTAL, LRSAM1, RIFLE, TAL, Tsg101 associated ligase
Background LRSAM1 抗体

LRSAM1 also named as hTAL, RIFLE orTsg101 associated ligase is a 723 amino acid protein, which contains 6 LRR repeats, 1 Ring-type zinc finger and 1 SAM domain. LRSAM1 is localizes in cytoplasm and highly expressed in adult spinal cord motoneurons as well as in fetal spinal cord and muscle tissue. As a E3 ubiquitin protein ligase, LRSAM1 mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic and exocytic cargos, LRSAM1 gene mutation has an association with Charcot Maire Tooth disease 2P. LRSAM1 抗体

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