FBXO24,FBXO24蛋白抗体

产品编号HZ-9090R
英文名称FBXO24
中文名称FBXO24蛋白抗体
别 名F box only protein 24; F box protein 24; F box protein Fbx24; F-box only protein 24; FBX24; FBX24_HUMAN; FBXO24.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 信号转导
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
FBXO24,FBXO24蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量65kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human FBXO24
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
FBXO24,FBXO24蛋白抗体PubMedPubMed
产品介绍background:
FBXO24 is a member of the F box protein family which is characterized by an approximately 40 amino acid motif, the F box. The F box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation dependent ubiquitination. There are 2 isoforms produced by alternative splicing.

Function:
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex (By similarity).

Subunit:
Directly interacts with SKP1 and CUL1 (By similarity).

Similarity:
Contains 1 F-box domain.
Contains 1 RCC1 repeat.

Gene ID:
26261

Database links:
Entrez Gene: 26261 Human
Entrez Gene: 71176 Mouse
Entrez Gene: 304374 Rat
Omim: 609097 Human
SwissProt: O75426 Human
SwissProt: Q9D417 Mouse
Unigene: 283764 Human
Unigene: 474695 Mouse

FBXO24,FBXO24蛋白抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.