NFAT5,活化T细胞核因子5蛋白抗体-抗体-抗体-生物在线
NFAT5,活化T细胞核因子5蛋白抗体

NFAT5,活化T细胞核因子5蛋白抗体

商家询价

产品名称: NFAT5,活化T细胞核因子5蛋白抗体

英文名称: Anti-NFAT5 antibody

产品编号: HZ-9473R

产品价格: null

产品产地: 中国/美国

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: WB,ELISA,IHC-P,IHC-F,IF

上海沪震实业有限公司
  • 联系人 : 鲍丽雯
  • 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
  • 邮编 : 200612
  • 所在区域 : 上海
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  • 邮箱 : www.shzbio.net

NFAT5,活化T细胞核因子5蛋白抗体

产品编号HZ-9473R
英文名称NFAT5
中文名称活化T细胞核因子5蛋白抗体
别 名Glutamine rich protein H65; KIAA0827; NF AT5; NF-AT5; NFAT 5; NFAT L1; NFAT like protein 1; NFAT5; NFAT5_HUMAN; NFATL 1; NFATL1; NFATZ; Nuclear factor of activated T cells 5; Nuclear factor of activated T cells 5 tonicity responsive; Nuclear factor of activated T cells; Nuclear factor of activated T-cells 5; OREBP; Osmotic response element binding protein; T cell transcription factor NFAT 5; T cell transcription factor NFAT5; T-cell transcription factor NFAT5; TonE binding protein; TonE-binding protein ; TonEBP; Tonicity responsive enhancer binding protein; Tonicity-responsive enhancer-binding protein
说 明 书0.1ml 0.2ml
研究领域心血管 转录调节因子 淋巴细胞 t-淋巴细胞 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
NFAT5,活化T细胞核因子5蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量166kDa
细胞定位细胞核
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human NFAT5
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
NFAT5,活化T细胞核因子5蛋白抗体PubMedPubMed
产品介绍background:
The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene.

Function:
Plays a role in the inducible expression of genes. Regulates hypertonicity-induced cellular accumulation of osmolytes.

Subunit:
Homodimer when bound to DNA, completely encircles its DNA target. Does not bind with Fos and Jun transcription factors.

Subcellular Location:
Nucleus.

Tissue Specificity:
Highest levels in skeletal muscle, brain, heart and peripheral blood leukocytes. Also expressed in placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine and colon.

NFAT5,活化T细胞核因子5蛋白抗体Post-translational modifications:
Phosphorylated at Thr-135 by CDK5 in response to osmotic stress; this phosphorylation mediates its rapid nuclear localization.

Similarity:
Contains 1 RHD (Rel-like) domain.

Database links:
Entrez Gene: 10725 Human
Entrez Gene: 54446 Mouse
Entrez Gene: 307820 Rat
Omim: 604708 Human
SwissProt: O94916 Human
SwissProt: Q9WV30 Mouse
Unigene: 371987 Human
Unigene: 390057 Mouse

NFAT5,活化T细胞核因子5蛋白抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.