XTP4,乙型肝炎病毒X蛋白反转录蛋白4抗体

产品编号HZ-9636R
英文名称XTP4
中文名称乙型肝炎病毒X蛋白反转录蛋白4抗体
别 名C17orf37; C35 antibody chromosome 17 open reading frame 37; HBV X transactivated gene 4 protein; HBV X-transactivated gene 4 protein; HBV XAg transactivated protein 4; HBV XAg-transactivated protein 4; MGC14832; Mien1; MIEN1_HUMAN; Migration and invasion enhancer 1; ORB3; Protein C35; RDX12.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 转录调节因子 细菌及病毒
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
XTP4,乙型肝炎病毒X蛋白反转录蛋白4抗体产品应用ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量12kDa
细胞定位细胞浆 细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human XTP4
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
XTP4,乙型肝炎病毒X蛋白反转录蛋白4抗体PubMedPubMed
产品介绍background:
Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process.

Function:
Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process.

Subunit:
Interacts with GPX1 (By similarity).

Subcellular Location:
Cellular localizationCytoplasm; cytosol. Cell membrane. Concentrates at the leading edge of migrating cells. Localizes outside membrane raft regions.

Tissue Specificity:
Among normal tissues, present only in Leydig cells. Strongly up-regulated in breast cancers and in brain cancer distant metastasis (at protein level). Up-regulated in prostate cancer cells and in the higher grades of prostate adenocarcinoma (at protein level).

Post-translational modifications:
Isoprenylation facilitates association with the plasma membrane and enhances the migratory phenotype of cells by inducing increased filopodia formation.

Similarity:
Belongs to the SelWTH family.

Database links:
Entrez Gene: 84299 Human
Entrez Gene: 103742 Mouse
Entrez Gene: 360617 Rat
Omim: 611802 Human
SwissProt: Q9BRT3 Human
SwissProt: Q9CQ86 Mouse
Unigene: 333526 Human
Unigene: 259614 Mouse
Unigene: 143893 Rat

XTP4,乙型肝炎病毒X蛋白反转录蛋白4抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.