FITC标记的胰岛β细胞生长因子Reg IIIα 抗体
产品名称： FITC标记的胰岛β细胞生长因子Reg IIIα 抗体
英文名称： Anti-Reg3 beta/FITC
产品编号： HZ-4911R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
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Rabbit Anti-Reg3 beta/FITC Conjugated antibody
FITC标记的胰岛β细胞生长因子Reg IIIα 抗体
| 产品编号 | bs-4911R-FITC |
| 英文名称 | Anti-Reg3 beta/FITC |
| 中文名称 | FITC标记的胰岛β细胞生长因子Reg IIIα 抗体 |
| 别 名 | Pap; Pap1; REG3B_MOUSE; Regenerating islet-derived protein 3-beta; REG-3-beta; Pancreatitis-associated protein 1; Regenerating islet-derived protein III-beta; Reg III-beta. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, Rat, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 16kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse Reg3 beta |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The regeneration (REG) family consists of secretory proteins involved in liver, pancreatic, gastric and intestinal cell proliferation or differentiation. Members of the REG family are divided into four subclasses, designated types I, II, III and IV. They have been implicated in the regulation of cell growth, tumorigenesis and the progression of cancer. Specifically, increased expression of Reg III Alpha results in pancreatic inflammation and liver carcinogenesis. Reg III Alpha, also de-signated pancreatitis-associated protein, localizes to the apical region of pancreatic acinar cells and is similar to the C-type lectin superfamily. The Reg III Alpha protein is mainly expressed in the intestine, with lower expression detected in healthy pancreas. It is also detected in pancreatic juice as a result of pancreatic inflammation. Function: Might be a stress protein involved in the control of bacterial proliferation. Subcellular Location: Secreted. Found in the apical region of pancreatic acinar cells. Tissue Specificity: Constitutively expressed in the small intestine, moderately in colon and at an extremely low level in healthy pancreas. DISEASE: Note=Overexpressed during the acute phase of pancreatitis. Similarity: Contains 1 C-type lectin domain. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
再生（ReG）家族由参与肝脏、胰腺、胃和肠细胞增殖或分化的分泌蛋白组成。REG家族的成员分为四个亚类，即I型、II型、III型和IV型。它们参与了细胞生长、肿瘤发生和癌症进展的调控。具体而言，RIG IIIα的表达增加导致胰腺炎症和肝癌发生。RegⅢα，也不是退行性胰腺炎相关蛋白，定位于胰腺腺泡细胞的顶端区域，与C型凝集素超家族相似。RegⅢα蛋白主要表达于肠道，在健康胰腺中表达较低。胰腺炎症也可检测到胰液中的炎症。