性能参数
产品名称： FITC标记的沉默驱动蛋白KIF4A抗体
英文名称： Anti-KIF4A/FITC
抗体货号： HZ-7107R-FITC
产品规格： 100ul
级 别： 分析纯, , 分析纯,
产品产地： 中国/上海
品牌商标： HZbscience
价 格： 2980元
抗原： Rabbit
抗原来源： Rabbit
抗体来源： Rabbit
适用物种：
FITCconjugate：FITC
应用范围： IF=1:50-200
更新时间： 2020/11/23 13:35:00
详细资料：
实验方法技术资料
浏览人数：247
供应商： 上海沪震实业有限公司
诚信指数：13682点
了解更多：进入公司展台
使用范围：仅限科研使用，不能应用于临床
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生物在线声明：以上所展示的信息由企业自行提供，内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。
产品详细描述
Rabbit Anti-KIF4A/FITC Conjugated antibody
FITC标记的沉默驱动蛋白KIF4A抗体
| 英文名称 | Anti-KIF4A/FITC |
| 中文名称 | FITC标记的沉默驱动蛋白KIF4A抗体 |
| 别 名 | Chromokinesin; Chromokinesin-A; Chromosome associated kinesin KIF4A; Chromosome-associated kinesin KIF4A; KIF4; KIF4 G1; KIF4-G1; KIF4A; KIF4A_HUMAN; Kinesin family member 4A. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 染色质和核信号 信号转导 细胞凋亡 细胞周期蛋白 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 140kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KIF4A |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization. Tissue specificity: Highly expressed in hematopoietic tissues, fetal liver, spleen, thymus and adult thymus and bone marrow. Lower levels are found in heart, testis, kidney, colon and lung. Function: Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization. Subunit: Interacts with unphosphorylated PRC1 during late mitosis. Subcellular Location: Nucleus matrix. Cytoplasm, cytoskeleton, spindle. Midbody. Chromosome. Note=Not present in the nucleolus. In early mitosis, associated with the mitotic spindle, in anaphase, localized to the spindle midzone and, in telophase and cytokinesis, to the midbody. In late cytokinesis, found in the center of the midbody. Associated with chromosomes at all stages of mitosis. Tissue Specificity: Highly expressed in hematopoietic tissues, fetal liver, spleen, thymus and adult thymus and bone marrow. Lower levels are found in heart, testis, kidney, colon and lung. Similarity: Belongs to the kinesin-like protein family. Chromokinesin subfamily. Contains 1 kinesin-motor domain. Database links: Entrez Gene: 24137 Human Entrez Gene: 16571 Mouse Entrez Gene: 84393 Rat NCBI: 7305205 Human Omim: 300521 Human SwissProt: O95239 Human SwissProt: P33174 Mouse Unigene: 648326 Human Unigene: 383091 Mouse Unigene: 231889 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
在中期至后期转变过程中，PrC1转位到叉指纺锤体微管端部的运动蛋白，这是形成有组织的中心纺锤体中段和中段和成功胞质分裂的重要步骤。可能在有丝分裂染色体定位和双极纺锤体稳定中发挥作用。
组织特异性：在造血组织、胎儿肝脏、脾脏、胸腺和***胸腺和骨髓中高表达。在心脏、睾丸、肾脏、结肠和肺中发现较低水平。
生物在线声明：以上所展示的信息由企业自行提供，内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。
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