FITC标记的肌萎缩Dystrobrevin β蛋白抗体
产品名称: FITC标记的肌萎缩Dystrobrevin β蛋白抗体
英文名称: Anti-DTNB/FITC
产品编号: HZ-3548R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-DTNB/FITC Conjugated antibody
FITC标记的肌萎缩Dystrobrevin β蛋白抗体
英文名称 | Anti-DTNB/FITC |
中文名称 | FITC标记的肌萎缩Dystrobrevin β蛋白抗体 |
别 名 | Beta dystrobrevin; Beta-dystrobrevin; DTN B; DTN-B; Dtnb; DTNB_HUMAN; Dystrobrevin beta; MGC17163; MGC57126. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 免疫学 信号转导 细胞骨架 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 71kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human DTNB (271-310aa) |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Dystrobrevin beta is a component of the dystrophin-associated protein complex and interacts with dystrophin short form DP71, syntrophins SNTG1 and SNTG2. It localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. 4 isoforms produced by alternative splicing have been identified. Subunit: Interacts with dystrophin short form DP71 and syntrophins SNTG1 and SNTG2. Binds dystrobrevin binding protein 1 (By similarity). Subcellular Location: Cytoplasm. Tissue Specificity: Highly expressed in brain, kidney and pancreas. Similarity: Belongs to the dystrophin family. Dystrobrevin subfamily. Contains 1 ZZ-type zinc finger. Database links: Entrez Gene: 1838 Human Entrez Gene: 13528 Mouse Omim: 602415 Human SwissProt: O60941 Human SwissProt: O70585 Mouse Unigene: 307720 Human Unigene: 286202 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
DestrRuvinβ是肌营养不良蛋白相关蛋白复合物的一个组成部分,与肌营养不良蛋白短型DP7A、合成酶SNTG1和SNTG2相互作用。它定位于肌膜,其破坏与各种形式的肌营养不良有关。已鉴定出4种由选择性剪接产生的异构体。