FITC标记的凋亡相关蛋白激酶样蛋白1抗体
产品名称： FITC标记的凋亡相关蛋白激酶样蛋白1抗体
英文名称： Anti-DAPL1/FITC
产品编号： HZ-12981R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
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Rabbit Anti-DAPL1/FITC Conjugated antibody
FITC标记的凋亡相关蛋白激酶样蛋白1抗体
| 英文名称 | Anti-DAPL1/FITC |
| 中文名称 | FITC标记的凋亡相关蛋白激酶样蛋白1抗体 |
| 别 名 | dapL1; DAPL1_HUMAN; death associated protein-like 1; Death-associated protein-like 1; Early epithelial differentiation-associated protein; EEDA; RP23-151F21.4. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 细胞凋亡 激酶和磷酸酶 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Horse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 12kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DAPL1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: In contrast to growth factors which promote cell proliferation, FAS ligand (FAS-L) and the tumor necrosis factors (TNFs) rapidly induce apoptosis. Cellular response to FAS-L and TNF is mediated by structurally related receptors containing a conserved cytoplasmic region called the “death domain”. DAPL1 (Death-associated protein-like 1), also known as EEDA (Early epithelial differentiation-associated protein), is a 107 amino acid protein that is expressed in hair follicles and is thought to function in a similar manner to DAP-1, possibly participating in the early stages of epithelial differentiation and/or apoptosis. Function: May play a role in the early stages of epithelial differentiation or in apoptosis. Tissue Specificity: Expressed in hair follicle (at protein level). Database links: Entrez Gene: 92196 Human Entrez Gene: 76747 Mouse SwissProt: A0PJW8 Human SwissProt: Q9D757 Mouse Unigene: 59761 Human Unigene: 275769 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
与促进细胞增殖的生长因子相比，FAS配体（FAS-L）和肿瘤坏死因子（TNF）能迅速诱导细胞凋亡。细胞对FAS-L和TNF的反应是由结构相关的受体介导的，这些受体包含一个叫做“死亡域”的保守细胞质区域。DAPL1(死亡相关蛋白样1)，也称为EEDA(早期上皮分化相关蛋白)，是一种107个氨基酸的蛋白质，在毛囊中表达，被认为以与DAP-1相似的方式起作用，可能参与上皮分化的早期阶段。和/或细胞凋亡。