FITC标记的强直性肌营养不良相关蛋白9抗体
产品名称： FITC标记的强直性肌营养不良相关蛋白9抗体
英文名称： Anti-DMWD/FITC
产品编号： HZ-13042R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
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- 邮箱 : www.shzbio.net
Rabbit Anti-DMWD/FITC Conjugated antibody
| FITC标记的强直性肌营养不良相关蛋白9抗体 |
| 英文名称 | Anti-DMWD/FITC |
| 中文名称 | FITC标记的强直性肌营养不良相关蛋白9抗体 |
| 别 名 | dystrophia myotonica containing WD repeat motif; D19S593E; DM 9; DM9; DMR N9; DMR N9 protein; DMRN 9; DMRN9; DMWD; DMWD_HUMAN; Dystrophia myotonica containing WD repeat motif; Dystrophia myotonica containing WD repeat motif protein; Dystrophia myotonica WD repeat containing protein; Dystrophia myotonica WD repeat-containing protein; Dystrophia myotonica-containing WD repeat motif protein; Gene59; Protein 59; Protein DMR-N9. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Cow, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 70kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DMWD/DMRN9 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: DMWD is a 674 amino acid protein containing five WD repeats. DMWD may play a role in the development of mental symptoms in severe cases of myotonic dystrophy, a chronic multisystemic disease characterized by wasting of the muscles, heart conduction defects, cataracts, endocrine changes and myotonia. The DMWD gene is located upstream of the DMPK gene and is prominently expressed in tissues affected in myotonic dystrophy patients. DMWD may also contribute to regulation in meiosis. DMWD is expressed in kidney and spleen, with strongest expression in brain, liver and testis. The gene encoding DMWD maps to human chromosome 19q13.32 and mouse chromosome 7 A3. Function: Could have a regulatory function in meiosis. Subcellular Location: Contains 5 WD repeats. Tissue Specificity: Strongest expression in brain, liver, and testis. Also expressed in kidney and spleen. Similarity: Contains 5 WD repeats. Database links: Entrez Gene: 1762 Human Omim: 609857 Human SwissProt: Q09019 Human Unigene: 515474 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
DWD是含有五个WD重复序列的674个氨基酸的蛋白质。DMWD在严重肌强直性营养不良（一种以肌肉萎缩、心脏传导缺陷、白内障、内分泌改变和肌强直为特征的慢性多系统疾病）患者的精神症状发展中可能发挥作用。DMWD基因位于DMPK基因的上游，在强直性肌营养不良患者的组织中显著表达。DMWD也可能有助于减数分裂的调节。DWD在肾脏和脾脏中表达，在脑、肝和睾丸中表达最强。编码DWD的基因映射到人类染色体19q1332和小鼠染色体7 A3。