FITC标记的多发性外生骨疣样蛋白3抗体
产品名称： FITC标记的多发性外生骨疣样蛋白3抗体
英文名称： Anti-EXTL3/FITC
产品编号： HZ-13123R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-EXTL3/FITC Conjugated antibody
FITC标记的多发性外生骨疣样蛋白3抗体
| 英文名称 | Anti-EXTL3/FITC |
| 中文名称 | FITC标记的多发性外生骨疣样蛋白3抗体 |
| 别 名 | botv; DKFZp686C2342; Exostoses (multiple)-like 3; Exostoses-like 3; Exostosin-like 3; EXT-related protein 1; EXTL1L; EXTL3; EXTL3_HUMAN; EXTR1; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferas; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Hereditary multiple exostoses gene isolog; KIAA0519; Multiple exostosis-like protein 3; Putative tumor suppressor protein EXTL3; REG; Reg receptor; REGR; RPR. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 发育生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Horse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 105kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human EXTL3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: EXTL3 is a member of the EXT (hereditary multiple exostosin) gene family of tumor suppressors encoding glycosyltransferases involved in heparan sulfate (HS) biosynthesis. Within this family, the C-terminus is conserved between all members from C. elegans to vertebrates. EXTL3 is a ubiquitously expressed, developmentally regulated, single-pass type II membrane protein that localizes to the endoplasmic reticulum membrane. EXTL3 adds N-acetylglucosamine (GlcNAc) to the polysaccharide-protein linkage region and to the growing HS chain suggesting that it plays a role in both the initiation and elongation of HS chains. In addition, EXTL3 may act as a Reg receptor, binding Reg via its N-terminus. Function: Probable glycosyltransferase. Subcellular Location: Endoplasmic reticulum membrane. Tissue Specificity: Ubiquitous. Similarity: Belongs to the glycosyltransferase 47 family. Database links: UniProtKB/Swiss-Prot: O43909.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
EXTL3是EXT（遗传性多发性外皮抑素）基因家族的成员，其编码硫酸乙酰肝素（HS）生物合成中的糖基转移酶。在这个家族中，C端在线虫与脊椎动物的所有成员之间是保守的。EXTL3是一种广泛表达、发育调节的单程II型膜蛋白，定位于内质网膜。EXTL3将N-乙酰氨基葡萄糖(GlcNAc)添加到多糖-蛋白质连接区和生长中的HS链中，表明它在HS链的起始和伸长中起作用。此外，EXTL3可以作为ReG受体，通过其N-末端结合Reg。